Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 55246-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55246-1-AP, RRID:AB_10863291
- Product name
- CARM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CARM1 antibody (Cat. #55246-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway.
CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β.
Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
Osteocytes Enhance Osteogenesis by Autophagy-Mediated FGF23 Secretion Under Mechanical Tension.
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression.
Feng S, Cao H, Sui Y, Shen Z, Wu J, Ma R, Feng J
Thoracic cancer 2023 Mar;14(8):724-735
Thoracic cancer 2023 Mar;14(8):724-735
CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β.
Cao Y, Chen Z, Qin Z, Qian K, Liu T, Zhang Y
Acta biochimica et biophysica Sinica 2022 May 25;54(5):604-614
Acta biochimica et biophysica Sinica 2022 May 25;54(5):604-614
Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.
Wang Z, Chen S, Zhang Y, Su C, Liao Y, Zhang S, Ren Y, Ye F, Zeng C, Zhou G, Xian H, Zhang M
Journal of reproductive immunology 2022 Jun;151:103635
Journal of reproductive immunology 2022 Jun;151:103635
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
Wang C, Chen X, Liu X, Lu D, Li S, Qu L, Yin F, Luo H, Zhang Y, Luo Z, Cui N, Kong L, Wang X
European journal of medicinal chemistry 2022 Aug 5;238:114462
European journal of medicinal chemistry 2022 Aug 5;238:114462
Osteocytes Enhance Osteogenesis by Autophagy-Mediated FGF23 Secretion Under Mechanical Tension.
Xu H, Xia M, Sun L, Wang H, Zhang WB
Frontiers in cell and developmental biology 2021;9:782736
Frontiers in cell and developmental biology 2021;9:782736
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
Du P, Luo K, Li G, Zhu J, Xiao Q, Li Y, Zhang X
International journal of medical sciences 2021;18(15):3588-3598
International journal of medical sciences 2021;18(15):3588-3598
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Wang C, Qu L, Li S, Yin F, Ji L, Peng W, Luo H, Lu D, Liu X, Chen X, Kong L, Wang X
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Xu C, Cao H, Sui Y, Zhang H, Shi C, Wu J, Ma R, Feng J
Cancer cell international 2021 Jan 12;21(1):48
Cancer cell international 2021 Jan 12;21(1):48
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Cui J, Hu J, Ye Z, Fan Y, Li Y, Wang G, Wang L, Wang Z
Science bulletin 2019 Jul 30;64(14):986-997
Science bulletin 2019 Jul 30;64(14):986-997
Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.
Yang G, Zhou C, Wang R, Huang S, Wei Y, Yang X, Liu Y, Li J, Lu Z, Ying W, Li X, Jing N, Huang X, Yang H, Qiao Y
Cell reports 2019 Jan 8;26(2):302-312.e4
Cell reports 2019 Jan 8;26(2):302-312.e4
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression.
Wu G, Wen M, Sun L, Li H, Liu Y, Li R, Wu F, Yang R, Lin Y
RSC advances 2018 Nov 1;8(65):37117-37128
RSC advances 2018 Nov 1;8(65):37117-37128
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COS-7 cells were subjected to SDS PAGE followed by western blot with 55246-1-AP(CARM1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 55246-1-AP(CARM1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CARM1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CARM1. This antibody recognizes human,mouse,rat, monkey antigen. The CARM1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.