BS8307

antibody from Bioworld Technology, Inc

Targeting: IL11RA

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8307

Provider

Bioworld Technology, Inc

Product name

IL11RA polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human IL11RA.

Description

The pleiotropic cytokine, IL-11, has been shown to have proliferative and differentiation effects on lymphopoietic, myeloid and erythroid cells. IL-11 also has the inhibiting effect of repressing adipogenesis in vitro. The IL-11a receptor, IL-11Ra, is a member of the class I subgroup of the cytokine receptor family and exhibits structural similarity to the a subunits of the human ciliary neurotrophic factor (CNTF) and the mouse IL-6 receptor. It is speculated that the IL-11Ra regulates the proliferation and/or differentiation of skeletogenic progenitor and mesenchymal cells. Coexpression of gp130 and IL-11a is necessary for high affinity binding of IL-11 to IL-11Ra. It has also been found that coexpression of IL-11Ra and gp130 is required for proper stimulation of Ba/F3 cells to differentiate into macrophage in response to IL-11.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.