Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Blocking/Neutralizing [2]
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Validation data
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- Product number
- AF490 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-11 R alpha Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-11 R alpha in direct ELISAs and Western blots.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q64385
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes.
Krejci P, Prochazkova J, Bryja V, Jelinkova P, Pejchalova K, Kozubik A, Thompson LM, Wilcox WR
Cellular signalling 2009 Jan;21(1):151-60
Cellular signalling 2009 Jan;21(1):151-60
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by IL-11 and Neutralization by Mouse IL-11 R alpha Antibody. Recombinant Mouse IL-11 (Catalog # 418-ML) stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL-11 (0.3 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-11 R alpha Antigen Affinity-purified Polyclonal Antibody (Catalog # AF490). The ND50 is typically 2-6 µg/mL.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by IL-11 and Neutralization by Mouse IL-11 R alpha Antibody. Recombinant Mouse IL-11 (Catalog # 418-ML) stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL-11 (1 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-11 R alpha Antigen Affinity-purified Polyclonal Antibody (Catalog # AF490). The ND50 is typically 1-6 µg/mL.