Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17958-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17958-1-AP, RRID:AB_2234541
- Product name
- LOX antibody
- Antibody type
- Polyclonal
- Description
- LOX antibody (Cat. #17958-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression of LOX Suggests Poor Prognosis in Gastric Cancer.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Drug resistance evaluation in novel 3D in vitro model.
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Matrisome Provides a Supportive Microenvironment for Skin Functions of Diverse Species.
Pharmacological and genetic targeting of 5-lipoxygenase interrupts c-Myc oncogenic signaling and kills enzalutamide-resistant prostate cancer cells via apoptosis.
Markers of the pre-metastatic niche "knock on the door" of metastasis-free cervical lymph nodes in patients with oral cancer.
Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma.
Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Megakaryocytic leukemia 1 (MKL1) mediates high glucose induced epithelial-mesenchymal transition by activating LOX transcription.
Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.
Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development.
Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3β activation.
Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.
Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse.
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Zhu J, Luo C, Zhao J, Zhu X, Lin K, Bu F, Yu Z, Zou F, Zhu Z
Frontiers in medicine 2021;8:718986
Frontiers in medicine 2021;8:718986
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Drug resistance evaluation in novel 3D in vitro model.
Nowacka M, Sterzynska K, Andrzejewska M, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111536
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111536
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Li RF, Chen XY, Xu Y, Feng FC, He HL, Zhou XM
Journal of ethnopharmacology 2021 Apr 6;269:113761
Journal of ethnopharmacology 2021 Apr 6;269:113761
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Cai Q, Wang X, Wang S, Jin L, Ding J, Zhou D, Ma F
International journal of nanomedicine 2020;15:253-262
International journal of nanomedicine 2020;15:253-262
Matrisome Provides a Supportive Microenvironment for Skin Functions of Diverse Species.
Liu B, Zhang S, Wang W, Yun Z, Lv L, Chai M, Wu Z, Zhu Y, Ma J, Leng L
ACS biomaterials science & engineering 2020 Oct 12;6(10):5720-5733
ACS biomaterials science & engineering 2020 Oct 12;6(10):5720-5733
Pharmacological and genetic targeting of 5-lipoxygenase interrupts c-Myc oncogenic signaling and kills enzalutamide-resistant prostate cancer cells via apoptosis.
Monga J, Subramani D, Bharathan A, Ghosh J
Scientific reports 2020 Apr 20;10(1):6649
Scientific reports 2020 Apr 20;10(1):6649
Markers of the pre-metastatic niche "knock on the door" of metastasis-free cervical lymph nodes in patients with oral cancer.
Vered M, Shnaiderman-Shapiro A, Schiby G, Zlotogorski-Hurvitz A, Salo T, Yahalom R
Acta histochemica 2019 Nov;121(8):151447
Acta histochemica 2019 Nov;121(8):151447
Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma.
Saito T, Uzawa K, Terajima M, Shiiba M, Amelio AL, Tanzawa H, Yamauchi M
Journal of dental research 2019 May;98(5):517-525
Journal of dental research 2019 May;98(5):517-525
Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression.
Duan Z, Li L, Li Y
Journal of physiology and biochemistry 2019 Jun;75(2):135-142
Journal of physiology and biochemistry 2019 Jun;75(2):135-142
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Megakaryocytic leukemia 1 (MKL1) mediates high glucose induced epithelial-mesenchymal transition by activating LOX transcription.
Ding Y, Xu H, Li L, Yuan Y, Xu Y
Biochemical and biophysical research communications 2019 Feb 12;509(3):633-640
Biochemical and biophysical research communications 2019 Feb 12;509(3):633-640
Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.
Zlatic SA, Vrailas-Mortimer A, Gokhale A, Carey LJ, Scott E, Burch R, McCall MM, Rudin-Rush S, Davis JB, Hartwig C, Werner E, Li L, Petris M, Faundez V
Cell systems 2018 Mar 28;6(3):368-380.e6
Cell systems 2018 Mar 28;6(3):368-380.e6
Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
Liu Y, Wang G, Liang Z, Mei Z, Wu T, Cui A, Liu C, Cui L
Thoracic cancer 2018 Jul;9(7):785-793
Thoracic cancer 2018 Jul;9(7):785-793
Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development.
Sterzyńska K, Klejewski A, Wojtowicz K, Świerczewska M, Nowacka M, Kaźmierczak D, Andrzejewska M, Rusek D, Brązert M, Brązert J, Nowicki M, Januchowski R
International journal of molecular sciences 2018 Dec 23;20(1)
International journal of molecular sciences 2018 Dec 23;20(1)
Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3β activation.
Li C, Zhang J, Wu H, Li L, Yang C, Song S, Peng P, Shao M, Zhang M, Zhao J, Zhao R, Wu W, Ruan Y, Wang L, Gu J
Scientific reports 2017 Mar 27;7:45275
Scientific reports 2017 Mar 27;7:45275
Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.
Franzetti GA, Laud-Duval K, van der Ent W, Brisac A, Irondelle M, Aubert S, Dirksen U, Bouvier C, de Pinieux G, Snaar-Jagalska E, Chavrier P, Delattre O
Oncogene 2017 Jun 22;36(25):3505-3514
Oncogene 2017 Jun 22;36(25):3505-3514
Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.
Liu F, Wang Y, Xu J, Liu F, Hu R, Deng H
Archives of medical science : AMS 2016 Oct 1;12(5):959-967
Archives of medical science : AMS 2016 Oct 1;12(5):959-967
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
Jiang J, Sun A, Wang Y, Deng Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse.
Cowling RT, Yeo SJ, Kim IJ, Park JI, Gu Y, Dalton ND, Peterson KL, Greenberg BH
American journal of physiology. Heart and circulatory physiology 2014 Sep 1;307(5):H773-81
American journal of physiology. Heart and circulatory physiology 2014 Sep 1;307(5):H773-81
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Shu G, Mi X, Cai J, Zhang X, Yin W, Yang X, Li Y, Chen L, Deng X
Toxicology letters 2013 Oct 24;222(2):91-101
Toxicology letters 2013 Oct 24;222(2):91-101
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17958-1-AP(LOX antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 17958-1-AP(LOX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LOX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LOX. This antibody recognizes human, mouse antigen. The LOX antibody has been validated for the following applications: ELISA, WB, IHC analysis.