SSX3

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. [provided by RefSeq, Jul 2013]

Description

SSX family member 3

Tissue specificity

Tissue enriched (testis)

Subcell location

Nucleoplasm, Nucleoli

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (48346427 - 48356707)

Ensembl ID

ENSG00000165584  (ver. 103.38)

Orthologs

-

UniProt

Q99909

neXtProt

NX_Q99909

Human splice variants

Protein structure