22692-1-AP

antibody from Proteintech Group

Targeting: HERC5 CEB1

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

22692-1-AP

Provider

Proteintech Group

Product name

HERC5 antibody

Antibody type

Polyclonal

Description

HERC5 antibody (Cat. #22692-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

E3 ligase HERC5-catalyzed UGDH isgylation promotes SNAI1-mediated tumor metastasis and cisplatin resistance in oral squamous cell carcinoma.

Zhang X, Liu F, Fang Q, Sun C, Fan J
Biology direct 2025 Mar 5;20(1):27

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HERC5-mediated ISGylation of SARS-CoV-2 nsp8 facilitates its degradation and inhibits viral replication.

Hou Y, Shi H, Wang H, Tian L, Huan C, Liu Y, Wang H, Zhang W
International journal of biological macromolecules 2025 Jun;315(Pt 2):144546

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Molecular Differences in Glomerular Compartment to Distinguish Immunoglobulin A Nephropathy and Lupus Nephritis.

Zhang H, Li S, Deng Z, Wang Y
Journal of inflammation research 2024;17:11357-11373

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Autophagy Deficiency Induced by SAT1 Potentiates Tumor Progression in Triple-Negative Breast Cancer.

Tian W, Zhu L, Luo Y, Tang Y, Tan Q, Zou Y, Chen K, Deng X, Tang H, Li H, Cai M, Xie X, Ye F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2309903

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ISGylation by HERCs facilitates STING activation.

Qin Y, Wang M, Meng X, Wang M, Jiang H, Gao Y, Li J, Zhao C, Han C, Zhao W, Zheng X
Cell reports 2024 May 28;43(5):114135

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Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction.

Vukić D, Cherian A, Keskitalo S, Bong YT, Marônek M, Yadav L, Keegan LP, Varjosalo M, O'Connell MA
Nucleic acids research 2024 Dec 11;52(22):14184-14204

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Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation.

Qin Y, Meng X, Wang M, Liang W, Xu R, Chen J, Song H, Fu Y, Li J, Gao C, Jia M, Zhao C, Zhao W
The Journal of clinical investigation 2023 Oct 16;133(20)

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Regulation of STING activity in DNA sensing by ISG15 modification.

Lin C, Kuffour EO, Fuchs NV, Gertzen CGW, Kaiser J, Hirschenberger M, Tang X, Xu HC, Michel O, Tao R, Haase A, Martin U, Kurz T, Drexler I, Görg B, Lang PA, Luedde T, Sparrer KMJ, Gohlke H, König R, Münk C
Cell reports 2023 Nov 28;42(11):113277

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ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53.

Osei Kuffour E, König R, Häussinger D, Schulz WA, Münk C
mBio 2019 Aug 27;10(4)

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ISG15 inhibits cancer cell growth and promotes apoptosis.

Zhou MJ, Chen FZ, Chen HC, Wan XX, Zhou X, Fang Q, Zhang DZ
International journal of molecular medicine 2017 Feb;39(2):446-452