Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 10-4044-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-IL-17RE Antibody
- Antibody type
- Monoclonal
- Description
- IL-17RE (Interleukin 17 receptor E) is an orphan receptor of the IL-17 receptor family. The members of this receptor family play a critical role in inflammatory responses and contribute to the pathology of many autoimmune diseases. IL-17RE is a receptor specific to IL-17C preferentially expressed on tissue epithelial cells and regulates early innate immunity to intestinal pathogens by signaling to downstream components of the mitogen activated protein kinase (MAPK) pathway.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant human
IL-17RE protein (amino acids 50-268
) was used as the immunogen for thi
s antibody.- Isotype
- IgG
- Antibody clone number
- ABM2G70
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of IL-17RE. Anti-IL-17RE antibody (Clone: ABM2G70) was tested at 2 µg/ml on (1) Jurkat, (2) PC3 and (3) NIH3T3 lysates.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular flow cytometric analysis of IL-17RE in human PBMC (Macrophage) using 2 µg/10^6 cells of Anti-IL-17RE antibody (10-4044 Abeomics) . Green represent isotype control and red represent Anti-IL-17RE antibody (Clone:ABM2G70). Goat anti-mouse PE conjugated secondary antibody (ABEOMICS) was used.
- Protocol
- Protocol