Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PB9933 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-CDCP1 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CDCP1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CDCP1 information: Molecular Weight: 92932 MW; Subcellular Localization: Isoform 1: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide; Tissue Specificity: Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Trimethylamine-N-oxide (TMAO) promotes balloon injury-induced neointimal hyperplasia via upregulating Beclin1 and impairing autophagic flux.
Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression.
Hong Q, Que D, Zhong C, Huang G, Zhai W, Chen D, Yan J, Yang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113639
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113639
Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression.
Roy BC, Ahmed I, Ramalingam S, Jala V, Haribabu B, Ramamoorthy P, Ashcraft J, Valentino J, Anant S, Sampath V, Umar S
Oncotarget 2019 Mar 22;10(24):2340-2354
Oncotarget 2019 Mar 22;10(24):2340-2354
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of CDCP1 expression in SW620 whole cell lysates (lane 1). CDCP1 at 130KD was detected using rabbit anti-CDCP1 Antigen Affinity purified polyclonal antibody (Catalog # PB9933) at 0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).
- Additional image