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Protein structure
NECAB3
N-terminal EF-hand calcium binding protein 3APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-B9705 |
Polyclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 18940-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| OriGene | AP33217PU-N |
Polyclonal |
WB
EL
ICC
IHC
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| Acris Antibodies GmbH | AP33217PU-N |
Polyclonal |
WB
EL
ICC
IHC
|
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| NovoPro Bioscience Inc. | 134386 |
Polyclonal |
WB
EL
ICC
IHC
|
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