Antibody data

Product number
BS60318 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Casein Kinase IÎÛ3 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human Casein Kinase IÎÛ3.
Description
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIÏ«, ÎÛ, š÷ and Ñ´, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an Ï«2ÉÇ2 or an Ï«Ï«ÉÇ2' structure. The Ï« catalytic subunit is stimulated by the ÉÇ regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CSNK1G3 protein structure - BS60318 shown in red.