Explore
Validate
Learn13683-1-AP
antibody from Proteintech Group
Targeting: CHMP4B
C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [52]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 13683-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CHMP4B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CHMP4B antibody (Cat. #13683-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gut microbiota-mediated activation of GSDMD ignites colorectal tumorigenesis.
TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress.
The human AAA-ATPase VPS4A isoform and its co-factor VTA1 have a unique function in regulating mammalian cytokinesis abscission.
Annexin A7 mediates lysosome repair independently of ESCRT-III.
Lysosomal Function and Intracellular Position Determine the Malignant Phenotype in Malignant Melanoma.
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy.
An oocyte meiotic midbody cap is required for developmental competence in mice.
Stress granules plug and stabilize damaged endolysosomal membranes.
Vps60 initiates alternative ESCRT-III filaments.
An oocyte meiotic midbody cap is required for developmental competence in mice.
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis.
DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.
Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway.
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons.
Mitochondrial calcium uniporter promotes phagocytosis-dependent activation of the NLRP3 inflammasome.
Long noncoding RNA Sh2d3c promotes manganese-induced neuronal apoptosis through the mmu-miR-675-5p/Chmp4b/Bax axis.
A function for ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission.
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
The Obligate Intracellular Bacterial Pathogen Anaplasma phagocytophilum Exploits Host Cell Multivesicular Body Biogenesis for Proliferation and Dissemination.
BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding.
Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair.
Ca(2+)-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair.
Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis.
Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation.
Rab11FIP1 maintains Rab35 at the intercellular bridge to promote actin removal and abscission.
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
LRRK2 activation controls the repair of damaged endomembranes in macrophages.
Loss of MLKL (Mixed Lineage Kinase Domain-Like Protein) Decreases Necrotic Core but Increases Macrophage Lipid Accumulation in Atherosclerosis.
Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins.
Human Cytomegalovirus Utilizes Extracellular Vesicles To Enhance Virus Spread.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Studying the Spatial Organization of ESCRTs in Cytokinetic Abscission Using the High-Resolution Imaging Techniques SIM and Cryo-SXT.
A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation.
A Septin Double Ring Controls the Spatiotemporal Organization of the ESCRT Machinery in Cytokinetic Abscission.
Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.
Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection.
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells.
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors.
ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome.
Recruitment of UBPY and ESCRT exchange drive HD-PTP-dependent sorting of EGFR to the MVB.
Chen J, Singh N, Ye X, Theune EV, Wang K
Cancer gene therapy 2024 Jul;31(7):1007-1017
Cancer gene therapy 2024 Jul;31(7):1007-1017
TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress.
Jeong E, Willett R, Rissone A, La Spina M, Puertollano R
Nature communications 2024 Jan 2;15(1):93
Nature communications 2024 Jan 2;15(1):93
The human AAA-ATPase VPS4A isoform and its co-factor VTA1 have a unique function in regulating mammalian cytokinesis abscission.
Dvilansky I, Altaras Y, Kamenetsky N, Nachmias D, Elia N
PLoS biology 2024 Apr;22(4):e3002327
PLoS biology 2024 Apr;22(4):e3002327
Annexin A7 mediates lysosome repair independently of ESCRT-III.
Ebstrup ML, Sønder SL, Fogde DL, Heitmann ASB, Dietrich TN, Dias C, Jäättelä M, Maeda K, Nylandsted J
Frontiers in cell and developmental biology 2023;11:1211498
Frontiers in cell and developmental biology 2023;11:1211498
Lysosomal Function and Intracellular Position Determine the Malignant Phenotype in Malignant Melanoma.
Eriksson I, Vainikka L, Wäster P, Öllinger K
The Journal of investigative dermatology 2023 Sep;143(9):1769-1778.e12
The Journal of investigative dermatology 2023 Sep;143(9):1769-1778.e12
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, Choi GE, Lee HJ, Han HJ
Autophagy 2023 Oct;19(10):2752-2768
Autophagy 2023 Oct;19(10):2752-2768
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy.
Nozawa T, Toh H, Iibushi J, Kogai K, Minowa-Nozawa A, Satoh J, Ito S, Murase K, Nakagawa I
Nature communications 2023 Oct 6;14(1):6230
Nature communications 2023 Oct 6;14(1):6230
An oocyte meiotic midbody cap is required for developmental competence in mice.
Schindler K, Jung GI, Londoño-Vásquez D, Park S, Skop A, Balboula A
Research square 2023 Oct 5;
Research square 2023 Oct 5;
Stress granules plug and stabilize damaged endolysosomal membranes.
Bussi C, Mangiarotti A, Vanhille-Campos C, Aylan B, Pellegrino E, Athanasiadi N, Fearns A, Rodgers A, Franzmann TM, Šarić A, Dimova R, Gutierrez MG
Nature 2023 Nov;623(7989):1062-1069
Nature 2023 Nov;623(7989):1062-1069
Vps60 initiates alternative ESCRT-III filaments.
Pfitzner AK, Zivkovic H, Bernat-Silvestre C, West M, Peltier T, Humbert F, Odorizzi G, Roux A
The Journal of cell biology 2023 Nov 6;222(11)
The Journal of cell biology 2023 Nov 6;222(11)
An oocyte meiotic midbody cap is required for developmental competence in mice.
Jung GI, Londoño-Vásquez D, Park S, Skop AR, Balboula AZ, Schindler K
Nature communications 2023 Nov 16;14(1):7419
Nature communications 2023 Nov 16;14(1):7419
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Wang F, Peters R, Jia J, Mudd M, Salemi M, Allers L, Javed R, Duque TLA, Paddar MA, Trosdal ES, Phinney B, Deretic V
Developmental cell 2023 May 22;58(10):866-884.e8
Developmental cell 2023 May 22;58(10):866-884.e8
Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis.
Jun YW, Lee S, Ban BK, Lee JA, Gao FB
Autophagy 2023 Jul;19(7):2045-2061
Autophagy 2023 Jul;19(7):2045-2061
DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.
Kumar R, Francis V, Ioannou MS, Aguila A, Khan M, Banks E, Kulasekaran G, McPherson PS
Cell reports 2023 Jul 25;42(7):112795
Cell reports 2023 Jul 25;42(7):112795
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.
Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B
Autophagy 2023 Dec;19(12):3132-3150
Autophagy 2023 Dec;19(12):3132-3150
Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.
Ogura M, Kaminishi T, Shima T, Torigata M, Bekku N, Tabata K, Minami S, Nishino K, Nezu A, Hamasaki M, Kosako H, Yoshimori T, Nakamura S
EMBO reports 2023 Dec 6;24(12):e57300
EMBO reports 2023 Dec 6;24(12):e57300
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway.
Tian J, Zhang YY, Peng YW, Liu B, Zhang XJ, Hu ZY, Hu CP, Luo XJ, Peng J
Journal of cardiovascular translational research 2022 Oct;15(5):1129-1142
Journal of cardiovascular translational research 2022 Oct;15(5):1129-1142
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons.
Goldsmith J, Ordureau A, Harper JW, Holzbaur ELF
Neuron 2022 Mar 16;110(6):967-976.e8
Neuron 2022 Mar 16;110(6):967-976.e8
Mitochondrial calcium uniporter promotes phagocytosis-dependent activation of the NLRP3 inflammasome.
Dong H, Zhao B, Chen J, Liu Z, Li X, Li L, Wen H
Proceedings of the National Academy of Sciences of the United States of America 2022 Jun 28;119(26):e2123247119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jun 28;119(26):e2123247119
Long noncoding RNA Sh2d3c promotes manganese-induced neuronal apoptosis through the mmu-miR-675-5p/Chmp4b/Bax axis.
Lu W, Li D, Wei S, Yang J, Tang C, Ma X, Zou Y
Toxicology letters 2022 Jul 15;365:24-35
Toxicology letters 2022 Jul 15;365:24-35
A function for ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission.
Luessing J, Okowa CC, Brennan E, Voisin M, Lowndes NF
iScience 2022 Jul 15;25(7):104536
iScience 2022 Jul 15;25(7):104536
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
Liu CC, Liu YY, Zhou JF, Chen X, Chen H, Hu JH, Chen J, Zhang J, Sun RC, Wei JC, Go YY, Morita E, Zhou B
PLoS pathogens 2022 Feb;18(2):e1010294
PLoS pathogens 2022 Feb;18(2):e1010294
The Obligate Intracellular Bacterial Pathogen Anaplasma phagocytophilum Exploits Host Cell Multivesicular Body Biogenesis for Proliferation and Dissemination.
Read CB, Lind MCH, Chiarelli TJ, Izac JR, Adcox HE, Marconi RT, Carlyon JA
mBio 2022 Dec 20;13(6):e0296122
mBio 2022 Dec 20;13(6):e0296122
BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding.
Wang M, Zhao K, Liu M, Wang M, Qiao Z, Yi S, Jiang Y, Kou X, Zhao Y, Yin J, Li T, Wang H, Jiang C, Gao S, Chen J
Protein & cell 2022 Aug;13(8):580-601
Protein & cell 2022 Aug;13(8):580-601
Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair.
Yim WW, Yamamoto H, Mizushima N
FEBS letters 2022 Apr;596(8):991-1003
FEBS letters 2022 Apr;596(8):991-1003
Ca(2+)-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair.
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM
Nature communications 2022 Apr 6;13(1):1875
Nature communications 2022 Apr 6;13(1):1875
Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis.
Andrade V, Bai J, Gupta-Rossi N, Jimenez AJ, Delevoye C, Lamaze C, Echard A
Science advances 2022 Apr 15;8(15):eabm5095
Science advances 2022 Apr 15;8(15):eabm5095
Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V
Cell 2021 Nov 24;184(24):5950-5969.e22
Cell 2021 Nov 24;184(24):5950-5969.e22
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation.
Parkinson G, Roboti P, Zhang L, Taylor S, Woodman P
Journal of cell science 2021 Nov 1;134(21)
Journal of cell science 2021 Nov 1;134(21)
Rab11FIP1 maintains Rab35 at the intercellular bridge to promote actin removal and abscission.
Iannantuono NVG, Emery G
Journal of cell science 2021 Jun 15;134(12)
Journal of cell science 2021 Jun 15;134(12)
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M
PLoS biology 2021 Jul;19(7):e3001361
PLoS biology 2021 Jul;19(7):e3001361
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Neggers JE, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Yang A, Kalekar RL, Krill-Burger JM, Dharia NV, Kugener G, Kalfon J, Yuan C, Dumont N, Gonzalez A, Abdusamad M, Li YY, Spurr LF, Wu WW, Durbin AD, Wolpin BM, Piccioni F, Root DE, Boehm JS, Cherniack AD, Tsherniak A, Hong AL, Hahn WC, Stegmaier K, Golub TR, Vazquez F, Aguirre AJ
Cell reports 2021 Jul 13;36(2):109367
Cell reports 2021 Jul 13;36(2):109367
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
Merigliano C, Burla R, La Torre M, Del Giudice S, Teo H, Liew CW, Chojnowski A, Goh WI, Olmos Y, Maccaroni K, Giubettini M, Chiolo I, Carlton JG, Raimondo D, Vernì F, Stewart CL, Rhodes D, Wright GD, Burke BE, Saggio I
PLoS genetics 2021 Aug;17(8):e1009757
PLoS genetics 2021 Aug;17(8):e1009757
LRRK2 activation controls the repair of damaged endomembranes in macrophages.
Herbst S, Campbell P, Harvey J, Bernard EM, Papayannopoulos V, Wood NW, Morris HR, Gutierrez MG
The EMBO journal 2020 Sep 15;39(18):e104494
The EMBO journal 2020 Sep 15;39(18):e104494
Loss of MLKL (Mixed Lineage Kinase Domain-Like Protein) Decreases Necrotic Core but Increases Macrophage Lipid Accumulation in Atherosclerosis.
Rasheed A, Robichaud S, Nguyen MA, Geoffrion M, Wyatt H, Cottee ML, Dennison T, Pietrangelo A, Lee R, Lagace TA, Ouimet M, Rayner KJ
Arteriosclerosis, thrombosis, and vascular biology 2020 May;40(5):1155-1167
Arteriosclerosis, thrombosis, and vascular biology 2020 May;40(5):1155-1167
Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins.
Eriksson I, Wäster P, Öllinger K
Cell death & disease 2020 May 14;11(5):370
Cell death & disease 2020 May 14;11(5):370
Human Cytomegalovirus Utilizes Extracellular Vesicles To Enhance Virus Spread.
Streck NT, Zhao Y, Sundstrom JM, Buchkovich NJ
Journal of virology 2020 Jul 30;94(16)
Journal of virology 2020 Jul 30;94(16)
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Neggers JE, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Yang A, Kalekar RL, Krill-Burger JM, Dharia NV, Kugener G, Kalfon J, Yuan C, Dumont N, Gonzalez A, Abdusamad M, Li YY, Spurr LF, Wu WW, Durbin AD, Wolpin BM, Piccioni F, Root DE, Boehm JS, Cherniack AD, Tsherniak A, Hong AL, Hahn WC, Stegmaier K, Golub TR, Vazquez F, Aguirre AJ
Cell reports 2020 Dec 15;33(11):108493
Cell reports 2020 Dec 15;33(11):108493
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
Studying the Spatial Organization of ESCRTs in Cytokinetic Abscission Using the High-Resolution Imaging Techniques SIM and Cryo-SXT.
Adar-Levor S, Goliand I, Elbaum M, Elia N
Methods in molecular biology (Clifton, N.J.) 2019;1998:129-148
Methods in molecular biology (Clifton, N.J.) 2019;1998:129-148
A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation.
Zhou Y, Bennett TM, Shiels A
Differentiation; research in biological diversity 2019 Sep-Oct;109:16-27
Differentiation; research in biological diversity 2019 Sep-Oct;109:16-27
A Septin Double Ring Controls the Spatiotemporal Organization of the ESCRT Machinery in Cytokinetic Abscission.
Karasmanis EP, Hwang D, Nakos K, Bowen JR, Angelis D, Spiliotis ET
Current biology : CB 2019 Jul 8;29(13):2174-2182.e7
Current biology : CB 2019 Jul 8;29(13):2174-2182.e7
Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.
Han Q, Lv L, Wei J, Lei X, Lin H, Li G, Cao J, Xie J, Yang W, Wu S, You J, Lu J, Liu P, Min J
Cancer letters 2019 Aug 10;457:47-59
Cancer letters 2019 Aug 10;457:47-59
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Liu S, Kwon M, Mannino M, Yang N, Renda F, Khodjakov A, Pellman D
Nature 2018 Sep;561(7724):551-555
Nature 2018 Sep;561(7724):551-555
iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.
Gao K, Zhang Y, Shi Q, Zhang J, Zhang L, Sun H, Jiao D, Zhao X, Tao H, Wei Y, Wang Y, Saiyin H, Zhao SM, Li Y, Zhang P, Wang C
Cell death & disease 2018 May 1;9(5):528
Cell death & disease 2018 May 1;9(5):528
Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection.
Streck NT, Carmichael J, Buchkovich NJ
Journal of virology 2018 Jun 15;92(12)
Journal of virology 2018 Jun 15;92(12)
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Goliand I, Adar-Levor S, Segal I, Nachmias D, Dadosh T, Kozlov MM, Elia N
Cell reports 2018 Aug 14;24(7):1756-1764
Cell reports 2018 Aug 14;24(7):1756-1764
Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells.
Kim SB, Kim HR, Park MC, Cho S, Goughnour PC, Han D, Yoon I, Kim Y, Kang T, Song E, Kim P, Choi H, Mun JY, Song C, Lee S, Jung HS, Kim S
The Journal of cell biology 2017 Jul 3;216(7):2201-2216
The Journal of cell biology 2017 Jul 3;216(7):2201-2216
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors.
Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M
Science signaling 2016 Jan 19;9(411):ra8
Science signaling 2016 Jan 19;9(411):ra8
ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome.
Flores-Rodriguez N, Kenwright DA, Chung PH, Harrison AW, Stefani F, Waigh TA, Allan VJ, Woodman PG
Journal of cell science 2015 Feb 15;128(4):755-67
Journal of cell science 2015 Feb 15;128(4):755-67
Recruitment of UBPY and ESCRT exchange drive HD-PTP-dependent sorting of EGFR to the MVB.
Ali N, Zhang L, Taylor S, Mironov A, Urbé S, Woodman P
Current biology : CB 2013 Mar 18;23(6):453-61
Current biology : CB 2013 Mar 18;23(6):453-61
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 13683-1-AP(CHMP4B antibody) at dilution of 1:200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human oesophagus cancer using 13683-1-AP(CHMP4B antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CHMP4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CHMP4B. This antibody recognizes human, mouse, rat antigen. The CHMP4B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
