BS6474

antibody from Bioworld Technology, Inc
Targeting: CACNG2 MGC138502, MGC138504, stargazin
Provider product page for BS6474
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6474 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CACNG2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CACNG2.
Description
Excitable cells in response to membrane depolarization are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha1 subunit, an intracellular beta subunit, a disulfide linked alpha2/delta subunit and a transmembrane gamma subunit. L-type Ca++ currents initiate muscle contraction, endocrine secretion and gene transcription, and are regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets. L-type calcium channels in the brain specifically express the gamma2 subunit along with gamma3 and gamma4 subunits. The gamma2 subunit (also known as stargazin) is abundant in synaptic plasma membranes where it regulates synaptic targeting of AMP receptors in granule cells.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CACNG2 protein structure - BS6474 shown in red.