Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- PA5-38043 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- betatrophin Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- A recommended positive control is rat liver tissue lysate. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Submitted references Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment.
Effects of vitamin D on apoptosis and betatrophin in the kidney tissue of experimental diabetic rats.
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
Arefanian H, Al-Khairi I, Khalaf NA, Cherian P, Kavalakatt S, Madhu D, Mathur A, Qaddoumi MG, Al-Mulla F, Abubaker J, Abu-Farha M
Lipids in health and disease 2021 Sep 26;20(1):117
Lipids in health and disease 2021 Sep 26;20(1):117
Effects of vitamin D on apoptosis and betatrophin in the kidney tissue of experimental diabetic rats.
Demircan S, Onalan E, Kuloğlu T, Aydın S, Yalçın MH, Gözel N, Dönder E
Acta bio-medica : Atenei Parmensis 2020 Sep 21;91(4):e2020089
Acta bio-medica : Atenei Parmensis 2020 Sep 21;91(4):e2020089
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
Chen S, Feng M, Zhang S, Dong Z, Wang Y, Zhang W, Liu C
Nature communications 2019 Aug 6;10(1):3518
Nature communications 2019 Aug 6;10(1):3518
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Fig. 5 Western blotting analysis of ANGPTL8 protein level in SAT, BAT and Liver measured at Day 0 (Control no cold exposure), Days 1, 5 and 10 post cold treatment at 4 0 C ( n = 2 for all groups). A : ANGPTL8 protein expression in SAT at different time points of cold treatment. B : ANGPTL8 protein expression in BAT at different time points of cold treatment. C : ANGPTL8 protein expression in Liver at different time points of cold treatment