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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 10227-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10227-1-AP, RRID:AB_2262043
- Product name
- EIF2S2 antibody
- Antibody type
- Polyclonal
- Description
- EIF2S2 antibody (Cat. #10227-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Termination of the integrated stress response.
Investigating the potential role of EIF2S2 in OSCC progression through comprehensive bioinformatics analysis and experimental validation.
Translation Initiation Factor-2S2 (eIF2S2) Contributes to Cervical Carcinogenesis by Inhibiting the TGF-β/SMAD4 Signaling Pathway.
Bi-allelic variants in chromatoid body protein TDRD6 cause spermiogenesis defects and severe oligoasthenoteratozoospermia in humans.
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
EIF2S2 transcriptionally upregulates HIF1α to promote gastric cancer progression via activating PI3K/AKT/mTOR pathway.
Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS.
Comprehensive Characterization of Ageing-Relevant Subtypes Associated With Different Tumorigenesis and Tumor Microenvironment in Prostate Cancer.
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.
Native purification of protein and RNA-protein complexes using a novel affinity procedure.
De Miguel C, Thorkelsson SR, Fatalska A, Hodgson G, Dalglish M, Wang C, Bertolotti A
Science (New York, N.Y.) 2026 Feb 19;391(6787):eadw5137
Science (New York, N.Y.) 2026 Feb 19;391(6787):eadw5137
Investigating the potential role of EIF2S2 in OSCC progression through comprehensive bioinformatics analysis and experimental validation.
Shao Z, Dong T, Yun K, Wang Z, Wen Y, Zhang Z, Jia T
European journal of medical research 2025 Jul 2;30(1):562
European journal of medical research 2025 Jul 2;30(1):562
Translation Initiation Factor-2S2 (eIF2S2) Contributes to Cervical Carcinogenesis by Inhibiting the TGF-β/SMAD4 Signaling Pathway.
Kundu J, Yang H, Moon S, Byun MR, Shin YK, Song K, Choi JS
Biomolecules & therapeutics 2024 Nov 1;32(6):767-777
Biomolecules & therapeutics 2024 Nov 1;32(6):767-777
Bi-allelic variants in chromatoid body protein TDRD6 cause spermiogenesis defects and severe oligoasthenoteratozoospermia in humans.
Guo R, Wu H, Zhu X, Wang G, Hu K, Li K, Geng H, Xu C, Zu C, Gao Y, Tang D, Cao Y, He X
Journal of medical genetics 2024 May 21;61(6):553-565
Journal of medical genetics 2024 May 21;61(6):553-565
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
Cao Z, Jing Y, Cheng C, Wang F, Guan M, Zhang K, Jiao J, Ruan L, Chen Z
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Qi Z, Bai X, Wu L, Zhang P, Guo Z, Yu Y
Journal of translational medicine 2024 Jun 6;22(1):538
Journal of translational medicine 2024 Jun 6;22(1):538
EIF2S2 transcriptionally upregulates HIF1α to promote gastric cancer progression via activating PI3K/AKT/mTOR pathway.
Wang Z, Zhang Y, Xue Y, Huang W, Zhang H
Carcinogenesis 2024 Dec 30;45(12):916-927
Carcinogenesis 2024 Dec 30;45(12):916-927
Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS.
Malik I, Tseng YJ, Wieland CM, Green KM, Zheng K, Calleja K, Todd PK
Neurobiology of disease 2023 Aug;184:106212
Neurobiology of disease 2023 Aug;184:106212
Comprehensive Characterization of Ageing-Relevant Subtypes Associated With Different Tumorigenesis and Tumor Microenvironment in Prostate Cancer.
Huang L, Xu Z, Xie Y, Jiang S, Han W, Tang Z, Zhu Q
Frontiers in molecular biosciences 2022;9:803474
Frontiers in molecular biosciences 2022;9:803474
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
Fittschen M, Lastres-Becker I, Halbach MV, Damrath E, Gispert S, Azizov M, Walter M, Müller S, Auburger G
Neurogenetics 2015 Jul;16(3):181-92
Neurogenetics 2015 Jul;16(3):181-92
Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.
Lee GY, Haverty PM, Li L, Kljavin NM, Bourgon R, Lee J, Stern H, Modrusan Z, Seshagiri S, Zhang Z, Davis D, Stokoe D, Settleman J, de Sauvage FJ, Neve RM
Cancer research 2014 Jun 1;74(11):3114-26
Cancer research 2014 Jun 1;74(11):3114-26
Native purification of protein and RNA-protein complexes using a novel affinity procedure.
Kroiss M, Brünger KM, Wiesner J, Grimmler M, Sickmann A, Fischer U
Fly 2009 Jul-Sep;3(3):221-8
Fly 2009 Jul-Sep;3(3):221-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 10227-1-AP(EIF2S2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using EIF2S2 antibody 10227-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10227-1-AP(EIF2S2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10227-1-AP(EIF2S2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
