Tissue expression
Cell line expression
Protein structure
ASIP
Agouti signaling proteinAGTIL, ASP
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NBP2-14323 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Bioworld Technology, Inc | BS8554 | Polyclonal |
WB
ICC
IHC
|
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Cusabio Biotech Co., Ltd | CSB-PA002212LA01HU | Polyclonal |
EL
ICC
IHC
|
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Biorbyt | orb2216363 | Polyclonal |
EL
ICC
IHC
|
||
antibodies-online | ABIN2561245 | Polyclonal |
WB
ICC
IHC
|
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