orb66850

antibody from Biorbyt

Targeting: KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21

Western blot (Data presented on provider website)

Antibody Data

Product number

orb66850

Provider

Biorbyt

Product name

MLL2 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to MLL2.MLL2 is a histone methyltransferase that methylates 'Lys-4' of histone H3 (H3K4me). H3K4merepresents a specific tag for epigenetic transcriptional activation. MLL2 plays a central role in betaglobinlocus transcription regulation by being recruited by NFE2. MLLS acts as a coactivator forestrogen receptor by being recruited by ESR1, thereby activating transcription. MLL2 is also requiredduring the transcriptionally active period of oocyte growth for the establishment and/or maintenance ofbulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption ofmeiosis, oocyte survival and normal zygotic genome activation.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C