DHH

gene product
HHG-3, MGC35145
This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010]
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antibodies-online
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Signalway Antibody LLC
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St John's Laboratory
1 antibody
Creative Diagnostics
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EMD Millipore
1 antibody
United States Biological
98 antibodies
Acris Antibodies GmbH
6 antibodies
Leading Biology
2 antibodies
ProSci
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
1 antibody