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Learn55047-1-AP
antibody from Proteintech Group
Targeting: ELAVL3
DKFZp547J036, HUC, HUCL, MGC20653, PLE21
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 55047-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55047-1-AP, RRID:AB_10859256
- Product name
- HuC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HuC antibody (Cat. #55047-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems.
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Nonsense-mediated decay masks cryptic splicing events caused by TDP-43 loss.
Machine learning-based proteomics profiling of ALS identifies downregulation of RPS29 that maintains protein homeostasis and STMN2 level.
Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes.
Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function.
Multi-omics revealed that ELAVL3 regulates MYCN in neuroblastoma via immunogenic cell death: Risk stratification and experimental research.
KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury.
Anaplastic Lymphoma Kinase Overexpression Is Associated with Aggressive Phenotypic Characteristics of Ovarian High-Grade Serous Carcinoma.
HuB and HuD repress telomerase activity by dissociating HuR from TERC.
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors.
Gao X, Li Y, Hu Y, Yang W, Peng L, Sheng J, Tian Y, Yao L, Zhao Y
Frontiers in nutrition 2025;12:1573516
Frontiers in nutrition 2025;12:1573516
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Zhang J, Huang X, Tang Y, Zhong X, Wang J, Wei M, Han X, Ke Y, Ba X
Communications biology 2025 Nov 30;9(1):3
Communications biology 2025 Nov 30;9(1):3
Nonsense-mediated decay masks cryptic splicing events caused by TDP-43 loss.
Zeng Y, Sianto O, Lovchykova A, Liu C, Akiyama T, Petrucelli L, Gitler AD
bioRxiv : the preprint server for biology 2025 Jul 9;
bioRxiv : the preprint server for biology 2025 Jul 9;
Machine learning-based proteomics profiling of ALS identifies downregulation of RPS29 that maintains protein homeostasis and STMN2 level.
Xu W, Guo Z, Guan Y, Lv S, Gao X, Luo W, Cheng T, Shao Z, Tao B, Wang T, Qiu Z
Communications biology 2025 Aug 7;8(1):1177
Communications biology 2025 Aug 7;8(1):1177
Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes.
Zhang X, Das T, Chao TF, Trinh V, Carmen-Orozco RP, Ling JP, Kalab P, Hayes LR
iScience 2024 Jun 21;27(6):110109
iScience 2024 Jun 21;27(6):110109
Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function.
Yang HZ, Zhuo D, Huang Z, Luo G, Liang S, Fan Y, Zhao Y, Lv X, Qiu C, Zhang L, Liu Y, Sun T, Chen X, Li SS, Jin X
Investigative ophthalmology & visual science 2024 Feb 1;65(2):31
Investigative ophthalmology & visual science 2024 Feb 1;65(2):31
Multi-omics revealed that ELAVL3 regulates MYCN in neuroblastoma via immunogenic cell death: Risk stratification and experimental research.
Hong P, Hu Z, Lin J, Cui K, Gao Z, Tian X, Shi Q, Lin T, Wei G
International journal of biological macromolecules 2024 Dec;282(Pt 4):137045
International journal of biological macromolecules 2024 Dec;282(Pt 4):137045
KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury.
Lai JD, Berlind JE, Fricklas G, Lie C, Urenda JP, Lam K, Sta Maria N, Jacobs R, Yu V, Zhao Z, Ichida JK
Cell stem cell 2024 Apr 4;31(4):519-536.e8
Cell stem cell 2024 Apr 4;31(4):519-536.e8
Anaplastic Lymphoma Kinase Overexpression Is Associated with Aggressive Phenotypic Characteristics of Ovarian High-Grade Serous Carcinoma.
Matsumoto T, Oda Y, Hasegawa Y, Hashimura M, Oguri Y, Inoue H, Yokoi A, Tochimoto M, Nakagawa M, Jiang Z, Saegusa M
The American journal of pathology 2021 Oct;191(10):1837-1850
The American journal of pathology 2021 Oct;191(10):1837-1850
HuB and HuD repress telomerase activity by dissociating HuR from TERC.
Cheng X, Gu X, Xia T, Ma Z, Yang Z, Feng HL, Zhao Y, Ma W, Ju Z, Gorospe M, Yi X, Tang H, Wang W
Nucleic acids research 2021 Mar 18;49(5):2848-2858
Nucleic acids research 2021 Mar 18;49(5):2848-2858
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
Diaz-Garcia S, Ko VI, Vazquez-Sanchez S, Chia R, Arogundade OA, Rodriguez MJ, Traynor BJ, Cleveland D, Ravits J
Acta neuropathologica 2021 Dec;142(6):985-1001
Acta neuropathologica 2021 Dec;142(6):985-1001
Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors.
Grassi E, Santoro R, Umbach A, Grosso A, Oliviero S, Neri F, Conti L, Ala U, Provero P, DiCunto F, Merlo GR
Frontiers in cellular neuroscience 2018;12:518
Frontiers in cellular neuroscience 2018;12:518
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 55047-1-AP(ELAVL3 antibody) at dilution of 1:200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ELAVL3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ELAVL3. This antibody recognizes human,mouse,rat antigen. The ELAVL3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
