Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5600 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ADH7 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ADH7.
- Description
- ADH7 (alcohol dehydrogenase 7 (class IV), Ã× or ¿¼ polypeptide), is a 386 amino acid protein belonging to the zinc-containing alcohol dehydrogenase family and the class-IV subfamily. Seven different human ADH isozymes exist: three belong to class-I: Ï«, ÉÇ and ÎÛ; one to class-II: Óð; one to class-III: í²; one to class-IV: ADH7; and one to class-V: ADH6. Encoded by a gene that maps to human chromosome 4q23, ADH7 localizes to the cytoplasm and is preferentially expressed in stomach, but, unlike other family members, is absent from liver. ADH7 is a homodimer that binds two zinc ions per subunit and contains nine exons. ADH7 participates in the synthesis of retinoic acid, a hormone important for cellular differentiation. Variations in ADH7 may be associated with alcohol dependence. ADH7 may also play a role in protection against aerodigestive tract cancer.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ADH7 pAb at 1:500 dilutionLane1:Hela cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate