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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10951-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10951-1-AP, RRID:AB_2163102
- Product name
- PDHX antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PDHX antibody (Cat. #10951-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Gastric cancer patient-derived organoids model for the therapeutic drug screening.
Low-dose deoxynivalenol exposure inhibits hepatic mitophagy and hesperidin reverses this phenomenon by activating SIRT1.
Singapore Grouper Iridovirus Induces Glucose Metabolism in Infected Cells by Activation of Mammalian Target of Rapamycin Signaling.
The Mitochondrial Ca(2+) import complex is altered in ADPKD.
Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma.
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Myocardin and pdx-1 synergistically induce hMSCs to differentiate into insulin secreting cells.
Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.
Auger JP, Zimmermann M, Faas M, Stifel U, Chambers D, Krishnacoumar B, Taudte RV, Grund C, Erdmann G, Scholtysek C, Uderhardt S, Ben Brahim O, Pascual Maté M, Stoll C, Böttcher M, Palumbo-Zerr K, Mangan MSJ, Dzamukova M, Kieler M, Hofmann M, Blüml S, Schabbauer G, Mougiakakos D, Sonnewald U, Hartmann F, Simon D, Kleyer A, Grüneboom A, Finotto S, Latz E, Hofmann J, Schett G, Tuckermann J, Krönke G
Nature 2024 May;629(8010):184-192
Nature 2024 May;629(8010):184-192
Gastric cancer patient-derived organoids model for the therapeutic drug screening.
Xu J, Gong J, Li M, Kang Y, Ma J, Wang X, Liang X, Qi X, Yu B, Yang J
Biochimica et biophysica acta. General subjects 2024 Apr;1868(4):130566
Biochimica et biophysica acta. General subjects 2024 Apr;1868(4):130566
Low-dose deoxynivalenol exposure inhibits hepatic mitophagy and hesperidin reverses this phenomenon by activating SIRT1.
Chen H, Xin W, Jiang J, Shan A, Ma J
Journal of hazardous materials 2024 Apr 15;468:133854
Journal of hazardous materials 2024 Apr 15;468:133854
Singapore Grouper Iridovirus Induces Glucose Metabolism in Infected Cells by Activation of Mammalian Target of Rapamycin Signaling.
Guo X, Zheng Q, Pan Z, Huang Y, Huang X, Qin Q
Frontiers in microbiology 2022;13:827818
Frontiers in microbiology 2022;13:827818
The Mitochondrial Ca(2+) import complex is altered in ADPKD.
Yanda MK, Tomar V, Cole R, Guggino WB, Cebotaru L
Cell calcium 2022 Jan;101:102501
Cell calcium 2022 Jan;101:102501
Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma.
Inoue J, Kishikawa M, Tsuda H, Nakajima Y, Asakage T, Inazawa J
Cancer science 2021 Jul;112(7):2792-2802
Cancer science 2021 Jul;112(7):2792-2802
Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
Liang C, Hao F, Yao X, Qiu Y, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Huang Y, Wu Y, Zheng L, Sun Y, Wang G, Yang X, Yang S, Sun L, Li Y
International journal of biological sciences 2019;15(7):1472-1487
International journal of biological sciences 2019;15(7):1472-1487
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Guo X, Wu S, Li N, Lin Q, Liu L, Liang H, Niu Y, Huang Z, Fu X
Biomolecules 2019 Sep 2;9(9)
Biomolecules 2019 Sep 2;9(9)
Myocardin and pdx-1 synergistically induce hMSCs to differentiate into insulin secreting cells.
Li JT, Sun FX
Biochemical and biophysical research communications 2014 Oct 6;
Biochemical and biophysical research communications 2014 Oct 6;
Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C
PloS one 2012;7(12):e50545
PloS one 2012;7(12):e50545
Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.
Lehner C, Gehwolf R, Wagner A, Resch H, Hirzinger C, Augat P, Stephan D, Aigner L, Rivera FJ, Bauer HC, Tempfer H
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2012 Jun;44(7):506-10
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2012 Jun;44(7):506-10
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 10951-1-AP(PDHX antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDHX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDHX. This antibody recognizes human,mouse,rat antigen. The PDHX antibody has been validated for the following applications: ELISA, WB, IHC analysis.
