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- References [18]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 60077-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60077-1-Ig, RRID:AB_2253445
- Product name
- RAC2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated RAC2 antibody (Cat. #60077-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C2H6
- Vial size
- 20ul, 150ul
Submitted references Xu Chunfu's Modified Xianglian Pill Regulates the NOX2/ROS/Mitochondria/NLRP3 Axis to Treat Ulcerative Colitis.
Macrophage efferocytosis mediated by the TP63-RAC2 pathway promotes immunosuppressive remodeling in esophageal cancer.
E3 ubiquitin ligase TRIM21-mediated K48-linked ubiquitination of ALDH2 rs671 mutant promotes adverse cardiac remodeling.
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
Novel analgesic peptide derived from Cinobufacini injection suppressing inflammation and pain via ERK1/2/COX-2 pathway.
Bruton's Tyrosine Kinase Inhibitors with Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling.
ADAM22 acts as a novel predictive biomarker for unfavorable prognosis and facilitates metastasis via PI3K/AKT signaling pathway in nasopharyngeal carcinoma.
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
DOCK2 regulates antifungal immunity by regulating RAC GTPase activity.
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
RAC2 acts as a prognostic biomarker and promotes the progression of clear cell renal cell carcinoma.
Rac signal adaptation controls neutrophil mobilization from the bone marrow.
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis.
Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
Mao S, Wang Y, Bu Q, Xu Z, Wei W, Wu D, Hu R, Wang C, Wang T, Yang Y
Pharmaceuticals (Basel, Switzerland) 2026 Mar 11;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Mar 11;19(3)
Macrophage efferocytosis mediated by the TP63-RAC2 pathway promotes immunosuppressive remodeling in esophageal cancer.
Xi Y, Zhao Z, Zhou Y, Yin C, Li Y, Xu X, Jin W, Lin C, Zhao K, Kuang J, Hong S, Yu B, Conde J, Liu S, Shen W
Cell reports. Medicine 2026 Jan 20;7(1):102529
Cell reports. Medicine 2026 Jan 20;7(1):102529
E3 ubiquitin ligase TRIM21-mediated K48-linked ubiquitination of ALDH2 rs671 mutant promotes adverse cardiac remodeling.
Han T, Wen X, Guo Y, Zhao X, Zhang J, Chen Y, Xu F
JCI insight 2026 Apr 8;11(7)
JCI insight 2026 Apr 8;11(7)
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
Yin H, Jiang H, Zhao R, Zhang Y, Fan X, Zhai X, Yang X, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
Novel analgesic peptide derived from Cinobufacini injection suppressing inflammation and pain via ERK1/2/COX-2 pathway.
Guo L, Zhang S, Zhang C, Ren S, Zhou Z, Wang F, Wang Y, Chen Q, Wang Y, Lee WH, Zhu K, Qin D, Gao Y, Sun T
International immunopharmacology 2024 Nov 15;141:112918
International immunopharmacology 2024 Nov 15;141:112918
Bruton's Tyrosine Kinase Inhibitors with Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling.
Li W, Sano R, Apatira M, DeAnda F, Gururaja T, Yang M, Lundgaard G, Pan C, Liu J, Zhai Y, Yoon WH, Wang L, Tse C, Souers AJ, Lee CH
Molecular cancer therapeutics 2024 Jan 3;23(1):35-46
Molecular cancer therapeutics 2024 Jan 3;23(1):35-46
ADAM22 acts as a novel predictive biomarker for unfavorable prognosis and facilitates metastasis via PI3K/AKT signaling pathway in nasopharyngeal carcinoma.
Xu K, Jiang P, Chen Z, Gu X, Zhang T
Pathology, research and practice 2024 Apr;256:155264
Pathology, research and practice 2024 Apr;256:155264
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Cheng T, Agwu C, Shim K, Wang B, Jain S, Mahjoub MR
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
DOCK2 regulates antifungal immunity by regulating RAC GTPase activity.
Ma X, Tan X, Yu B, Sun W, Wang H, Hu H, Du Y, He R, Gao R, Peng Q, Cui Z, Pan T, Feng X, Wang J, Xu C, Zhu B, Liu W, Wang C
Cellular & molecular immunology 2022 May;19(5):602-618
Cellular & molecular immunology 2022 May;19(5):602-618
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Xiong M, Zou L, Meng L, Zhang X, Tian Y, Zhang G, Yang J, Chen G, Xiong J, Ye K, Zhang Z
Progress in neurobiology 2021 Aug;203:102074
Progress in neurobiology 2021 Aug;203:102074
Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.
Kang Y, Liu J, Yin S, Jiang Y, Feng X, Wu J, Zhang Y, Chen A, Zhang Y, Shao L
ACS nano 2020 Mar 24;14(3):3059-3074
ACS nano 2020 Mar 24;14(3):3059-3074
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Zhang X, Fang J, Chen S, Wang W, Meng S, Liu B
Cancer medicine 2019 Sep;8(12):5716-5734
Cancer medicine 2019 Sep;8(12):5716-5734
RAC2 acts as a prognostic biomarker and promotes the progression of clear cell renal cell carcinoma.
Liu Y, Cheng G, Song Z, Xu T, Ruan H, Cao Q, Wang K, Bao L, Liu J, Zhou L, Liu D, Yang H, Chen K, Zhang X
International journal of oncology 2019 Sep;55(3):645-656
International journal of oncology 2019 Sep;55(3):645-656
Rac signal adaptation controls neutrophil mobilization from the bone marrow.
Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di Savino A, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E
Science signaling 2016 Dec 20;9(459):ra124
Science signaling 2016 Dec 20;9(459):ra124
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18
Oncotarget 2015 Aug 21;6(24):20404-18
Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR
The Journal of experimental medicine 2014 Sep 22;211(10):1957-68
The Journal of experimental medicine 2014 Sep 22;211(10):1957-68
The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis.
Cavnar PJ, Mogen K, Berthier E, Beebe DJ, Huttenlocher A
The Journal of biological chemistry 2012 Jul 20;287(30):25466-77
The Journal of biological chemistry 2012 Jul 20;287(30):25466-77
Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
Wang ZJ, Song L, Guo LC, Yin M, Sun YN
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):993-1000
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):993-1000
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 60077-1-Ig(RAC2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAC2 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human RAC2. This antibody recognizes human, mouse antigen. The RAC2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
