Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 60077-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60077-1-Ig, RRID:AB_2253445
- Product name
- RAC2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated RAC2 antibody (Cat. #60077-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C2H6
- Vial size
- 20ul, 150ul
Submitted references A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
RAC2 acts as a prognostic biomarker and promotes the progression of clear cell renal cell carcinoma.
Rac signal adaptation controls neutrophil mobilization from the bone marrow.
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis.
Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
Xiong M, Zou L, Meng L, Zhang X, Tian Y, Zhang G, Yang J, Chen G, Xiong J, Ye K, Zhang Z
Progress in neurobiology 2021 Aug;203:102074
Progress in neurobiology 2021 Aug;203:102074
Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.
Kang Y, Liu J, Yin S, Jiang Y, Feng X, Wu J, Zhang Y, Chen A, Zhang Y, Shao L
ACS nano 2020 Mar 24;14(3):3059-3074
ACS nano 2020 Mar 24;14(3):3059-3074
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Zhang X, Fang J, Chen S, Wang W, Meng S, Liu B
Cancer medicine 2019 Sep;8(12):5716-5734
Cancer medicine 2019 Sep;8(12):5716-5734
RAC2 acts as a prognostic biomarker and promotes the progression of clear cell renal cell carcinoma.
Liu Y, Cheng G, Song Z, Xu T, Ruan H, Cao Q, Wang K, Bao L, Liu J, Zhou L, Liu D, Yang H, Chen K, Zhang X
International journal of oncology 2019 Sep;55(3):645-656
International journal of oncology 2019 Sep;55(3):645-656
Rac signal adaptation controls neutrophil mobilization from the bone marrow.
Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di Savino A, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E
Science signaling 2016 Dec 20;9(459):ra124
Science signaling 2016 Dec 20;9(459):ra124
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18
Oncotarget 2015 Aug 21;6(24):20404-18
Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR
The Journal of experimental medicine 2014 Sep 22;211(10):1957-68
The Journal of experimental medicine 2014 Sep 22;211(10):1957-68
The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis.
Cavnar PJ, Mogen K, Berthier E, Beebe DJ, Huttenlocher A
The Journal of biological chemistry 2012 Jul 20;287(30):25466-77
The Journal of biological chemistry 2012 Jul 20;287(30):25466-77
Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
Wang ZJ, Song L, Guo LC, Yin M, Sun YN
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):993-1000
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):993-1000
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 60077-1-Ig(RAC2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAC2 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human RAC2. This antibody recognizes human, mouse antigen. The RAC2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.