HPA000527

antibody from Atlas Antibodies

Targeting: XPNPEP3 APP3, ICP55, NPHPL1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA000527

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA000527, RRID:AB_1079266

Product name

Anti-XPNPEP3

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human XPNPEP3, Gene description: X-prolyl aminopeptidase (aminopeptidase P) 3, putative, Alternative Gene Names: APP3, NPHPL1, Validated applications: WB, IHC, Uniprot ID: Q9NQH7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome

Rao S, Chen Q, Wang Q, Orth-He E, Saoi M, Griswold A, Bhattacharjee A, Ball D, Huang H, Chui A, Covelli D, You S, Cross J, Bachovchin D
Nature Chemical Biology 2022;18(5):565-574

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Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis.

Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galán-Echevarría F, Karz A, Argibay D, Von Itter R, Floristán A, Baptiste G, Eskow NM, Tranos JA, Chen J, Vega Y Saenz de Miera EC, Call M, Rogers R, Jour G, Wadghiri YZ, Osman I, Li YM, Mathews P, DeMattos RB, Ueberheide B, Ruggles KV, Liddelow SA, Schneider RJ, Hernando E
Cancer discovery 2022 May 2;12(5):1314-1335

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Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

O’Toole J, Liu Y, Davis E, Westlake C, Attanasio M, Otto E, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel L, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf M, Wise E, Helou J, Allen S, Murga-Zamalloa C, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins B, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac R, Quarmby L, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten J, Rotig A, Sayer J, Rolinski B, Freisinger P, Madhavan S, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson P, Khanna H, Katsanis N, Hildebrandt F
Journal of Clinical Investigation 2010;120(3):791-802