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- References [19]
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- Product number
- 12205-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12205-1-AP, RRID:AB_2256660
- Product name
- TRIM27 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM27 antibody (Cat. #12205-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LTN1 promotes RLR degradation to inhibit immune response to RNA virus through the ESCRT pathway.
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
Drosophila as Model System to Study Ras-Mediated Oncogenesis: The Case of the Tensin Family of Proteins.
MAGED4B Promotes Glioma Progression via Inactivation of the TNF-α-induced Apoptotic Pathway by Down-regulating TRIM27 Expression.
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1.
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
TRIM27 regulates the expression of PDCD4 by the ubiquitin‑proteasome pathway in ovarian and endometrial cancer cells.
Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression.
TRIM27-mediated ubiquitination of PPARγ promotes glutamate-induced cell apoptosis and inflammation.
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
TRIM28 and TRIM27 are required for expressions of PDGFRβ and contractile phenotypic genes by vascular smooth muscle cells.
The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer.
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway.
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes.
Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Qin F, Cai B, Wang P, Cao R, Zhang Y, Wen H, Zheng Y, Zhao W, Gao C, Liu B
Autophagy 2024 Jun;20(6):1270-1285
Autophagy 2024 Jun;20(6):1270-1285
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
Liu K, Gu Y, Gu S, Song L, Hua S, Li D, Tang M
International immunopharmacology 2024 Jun 15;134:112199
International immunopharmacology 2024 Jun 15;134:112199
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
Carden S, Vitiello E, Rosa E Silva I, Holder J, Quarantotti V, Kishore K, Roamio Franklin VN, D'Santos C, Ochi T, van Breugel M, Gergely F
Developmental cell 2023 Nov 6;58(21):2393-2410.e9
Developmental cell 2023 Nov 6;58(21):2393-2410.e9
Drosophila as Model System to Study Ras-Mediated Oncogenesis: The Case of the Tensin Family of Proteins.
Martínez-Abarca Millán A, Soler Beatty J, Valencia Expósito A, Martín-Bermudo MD
Genes 2023 Jul 23;14(7)
Genes 2023 Jul 23;14(7)
MAGED4B Promotes Glioma Progression via Inactivation of the TNF-α-induced Apoptotic Pathway by Down-regulating TRIM27 Expression.
Liu C, Liu J, Shao J, Huang C, Dai X, Shen Y, Hou W, Shen Y, Yu Y
Neuroscience bulletin 2023 Feb;39(2):273-291
Neuroscience bulletin 2023 Feb;39(2):273-291
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1.
Garcia-Garcia J, Berge AKM, Overå KS, Larsen KB, Bhujabal Z, Brech A, Abudu YP, Lamark T, Johansen T, Sjøttem E
The FEBS journal 2023 Feb;290(4):1096-1116
The FEBS journal 2023 Feb;290(4):1096-1116
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Zhou H, Feng W, Yu J, Shafiq TA, Paulo JA, Zhang J, Luo Z, Gygi SP, Moazed D
Cell reports 2023 Apr 25;42(4):112339
Cell reports 2023 Apr 25;42(4):112339
TRIM27 regulates the expression of PDCD4 by the ubiquitin‑proteasome pathway in ovarian and endometrial cancer cells.
Yu H, Wan L, Tang Z, Yao C, Zhang D, Jiang M, Wang C, Liu Y, Xue C, Wang X, Shi Y, Zhang L, Wang X, Wei Z
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression.
Zhao F, Li S, Liu J, Wang J, Yang B
Human cell 2022 Jul;35(4):1234-1247
Human cell 2022 Jul;35(4):1234-1247
TRIM27-mediated ubiquitination of PPARγ promotes glutamate-induced cell apoptosis and inflammation.
Hao Y, Bai S, Peng J, Hong R, Ding J, Li Z, Guan Y
Experimental cell research 2021 Mar 1;400(1):112437
Experimental cell research 2021 Mar 1;400(1):112437
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
TRIM28 and TRIM27 are required for expressions of PDGFRβ and contractile phenotypic genes by vascular smooth muscle cells.
Wang Y, Hao Y, Zhao Y, Huang Y, Lai D, Du T, Wan X, Zhu Y, Liu Z, Wang Y, Wang N, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6271-6283
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6271-6283
The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer.
Gibbs ZA, Reza LC, Cheng CC, Westcott JM, McGlynn K, Whitehurst AW
eLife 2020 Jun 9;9
eLife 2020 Jun 9;9
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
Xing L, Tang X, Wu K, Huang X, Yi Y, Huan J
Molecular therapy. Nucleic acids 2020 Dec 4;22:910-923
Molecular therapy. Nucleic acids 2020 Dec 4;22:910-923
TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway.
Ma L, Yao N, Chen P, Zhuang Z
Cancer cell international 2019;19:283
Cancer cell international 2019;19:283
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
Liu J, Feng X, Tian Y, Wang K, Gao F, Yang L, Li H, Tian Y, Yang R, Zhao L, Miao X, Huang J, Liu Q, Zhang W, Li Y, Wang C, Duan H, Liu S
Journal of cellular physiology 2019 Jul;234(7):11555-11566
Journal of cellular physiology 2019 Jul;234(7):11555-11566
Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes.
Wang T, Xia C, Dong Y, Chen X, Wang J, Du J
Journal of leukocyte biology 2018 Oct;104(4):799-809
Journal of leukocyte biology 2018 Oct;104(4):799-809
Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo.
Ma Y, Wei Z, Bast RC Jr, Wang Z, Li Y, Gao M, Liu Y, Wang X, Guo C, Zhang L, Wang X
Laboratory investigation; a journal of technical methods and pathology 2016 Jan;96(1):37-48
Laboratory investigation; a journal of technical methods and pathology 2016 Jan;96(1):37-48
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12205-1-AP(TRIM27 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRIM27 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRIM27. This antibody recognizes human, mouse, rat antigen. The TRIM27 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
