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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
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- Product number
- 648402 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#648402, RRID:AB_2257826
- Product name
- Purified anti-tartrate-resistant acid phosphatase (TRAcP)
- Antibody type
- Monoclonal
- Antigen
- TRAcP purified from hairy cell leukemia spleen tissue
- Description
- Serum tartrate-resistant acid phosphatase exists as two isoforms (TRAcP5a and 5b). They are derived by differential-posttranslational processing of a common gene. Serum TRAcP5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP5b is produced from osteoclasts and elevated during bone resorption. In addition, this antibody labels hairy leukemia cells with high degree of sensitivity and specificity.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C.
Submitted references Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis.
Toro EJ, Zuo J, Ostrov DA, Catalfamo D, Bradaschia-Correa V, Arana-Chavez V, Caridad AR, Neubert JK, Wronski TJ, Wallet SM, Holliday LS
The Journal of biological chemistry 2012 May 18;287(21):17894-904
The Journal of biological chemistry 2012 May 18;287(21):17894-904
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of recombinant human TRACP/PAP/ACP5 protein (lane 1) and PBMC (lane 2) using anti-TRACP antibody, clone 9C5.
- Conjugate
- Unconjugated
