V7300

antibody from NSJ Bioreagents

Targeting: LAIR1 CD305

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

V7300

Provider

NSJ Bioreagents

Product name

LAIR-1 Antibody

Antibody type

Monoclonal

Description

Protein G affinity chromatography

Reactivity

Human, Other

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

9.1C3

Vial size

20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)

Concentration

0.2 mg/ml, 1 mg/ml (BSA/azide free format), Prediluted (IHC only format)

Storage

Store the LAIR-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

References

Submitted references

LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-α stimulation.

Zhang Y, Wang S, Dong H, Yi X, Zhang J, Liu X, Zhuang R, Ding Y
Clinical and experimental immunology 2018 May;192(2):193-205

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Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPARγ and M2 polarization.

Yi X, Zhang J, Zhuang R, Wang S, Cheng S, Zhang D, Xie J, Hu W, Liu X, Zhang Y, Ding Y, Zhang Y
Cytokine 2018 Aug 31;111:194-205

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The role of LAIR-1 (CD305) in T cells and monocytes/macrophages in patients with rheumatoid arthritis.

Zhang Y, Lv K, Zhang CM, Jin BQ, Zhuang R, Ding Y
Cellular immunology 2014 Jan;287(1):46-52

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A non-stimulatory monoclonal antibody against the inhibitory immunoreceptor LAIR-1.

Xie X, Xu Z, Cui J, Jin B
Monoclonal antibodies in immunodiagnosis and immunotherapy 2014 Apr;33(2):141-7

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Development and evaluation of a sandwich ELISA method for the detection of human CD306.

Xie X, Wang C, Xie Y, Wang X, Chen G, Yan X, Cui J, Chen F, Li H, Jin B
Journal of immunological methods 2013 Oct 31;396(1-2):65-73

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Expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on osteoclasts and its potential role in rheumatoid arthritis.

Zhang Y, Ding Y, Huang Y, Zhang C, Boquan J, Ran Z
Clinics (Sao Paulo, Brazil) 2013 Apr;68(4):475-81

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Leukocyte-associated immunoglobulin-like receptor-1 is expressed on human megakaryocytes and negatively regulates the maturation of primary megakaryocytic progenitors and cell line.

Xue J, Zhang X, Zhao H, Fu Q, Cao Y, Wang Y, Feng X, Fu A
Biochemical and biophysical research communications 2011 Feb 4;405(1):128-33

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Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant.

Ouyang W, Xue J, Liu J, Jia W, Li Z, Xie X, Liu X, Jian J, Li Q, Zhu Y, Yang A, Jin B
Journal of immunological methods 2004 Sep;292(1-2):109-17

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9.1C3 is identical to LAIR-1, which is expressed on hematopoietic progenitors.

Ouyang W, Ma D, Lin D, Sun Y, Liu X, Li Q, Jia W, Cao Y, Zhu Y, Jin B
Biochemical and biophysical research communications 2003 Oct 31;310(4):1236-40