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- References [168]
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- Product number
- 17090-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17090-1-AP, RRID:AB_2142463
- Product name
- MFF antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MFF antibody (Cat. #17090-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Footprints of Mitochondrial Fission and Apoptosis in Fluoride-Induced Renal Dysfunction.
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo.
Inhibition of Drp1- Fis1 interaction alleviates aberrant mitochondrial fragmentation and acute kidney injury.
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion.
A Mammalian Conserved Circular RNA CircLARP1B Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism.
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Rescue of mitochondrial import failure by intercellular organellar transfer.
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity.
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Photobiomodulation provides neuroprotection through regulating mitochondrial fission imbalance in the subacute phase of spinal cord injury.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose.
Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons.
Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction.
S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis.
Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins.
Electroacupuncture alleviates multifidus muscle injury by modulating mitochondrial function and Ca(2+) uptake.
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner.
AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye.
Tissue Transglutaminase Knock-Out Preadipocytes and Beige Cells of Epididymal Fat Origin Possess Decreased Mitochondrial Functions Required for Thermogenesis.
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
PINK1 regulates mitochondrial fission/fusion and neuroinflammation in β-amyloid-induced Alzheimer's disease models.
Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria.
Regulatory roles of external cholesterol in human airway epithelial mitochondrial function through STARD3 signalling.
GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton.
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division.
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy.
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1.
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy.
Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy.
SENP3 Promotes an Mff-Primed Bcl-x (L) -Drp1 Interaction Involved in Cell Death Following Ischemia.
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity.
Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division.
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides.
Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway.
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson's disease-associated phenotypes in vivo.
The XBP1‒MARCH5‒MFN2 Axis Confers Endoplasmic Reticulum Stress Resistance by Coordinating Mitochondrial Fission and Mitophagy in Melanoma.
Diethyl Succinate Modulates Microglial Polarization and Activation by Reducing Mitochondrial Fission and Cellular ROS.
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy.
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation.
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Novel ultrastructural findings on cardiac mitochondria of huddling Brandt's voles in mild cold environment.
Protein Kinase C-δ Mediates Kidney Tubular Injury in Cold Storage-Associated Kidney Transplantation.
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet.
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.
Drp1/Mff signaling pathway is involved in fluoride-induced abnormal fission of hepatocyte mitochondria in mice.
Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer.
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.
Desferoxamine protects against glucocorticoid-induced osteonecrosis of the femoral head via activating HIF-1α expression.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer.
Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.
Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway.
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
Neuronal susceptibility to beta-amyloid toxicity and ischemic injury involves histone deacetylase-2 regulation of endophilin-B1.
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis.
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.
Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity.
Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior.
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.
Quantifying the inhibitory effect of Bcl-xl on the action of Mff using live-cell fluorescence imaging.
MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer.
Novel findings on ultrastructural protection of skeletal muscle fibers during hibernation of Daurian ground squirrels: Mitochondria, nuclei, cytoskeleton, glycogen.
MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress.
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
Clinical and Biochemical Features in a Patient With Mitochondrial Fission Factor Gene Alteration.
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Polybrene induces neural degeneration by bidirectional Ca(2+) influx-dependent mitochondrial and ER-mitochondrial dynamics.
A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission.
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.
TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue.
Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network.
Mitochondria elongation is mediated through SIRT1-mediated MFN1 stabilization.
Mechanical force induces mitochondrial fission.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death.
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease.
Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum.
The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1.
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes.
SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells.
Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission.
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis.
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein.
Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling.
Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin.
Correcting mitochondrial fusion by manipulating mitofusin conformations.
Multiple dynamin family members collaborate to drive mitochondrial division.
Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function.
COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1.
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate.
Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.
Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission.
AKAP350C targets to mitochondria via a novel amphipathic alpha helical domain.
Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons.
Loss of Yme1L perturbates mitochondrial dynamics.
Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c.
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
ER tubules mark sites of mitochondrial division.
Zuo Q, Lin L, Zhang Y, Ommati MM, Wang H, Zhao J
Biological trace element research 2024 Sep;202(9):4125-4135
Biological trace element research 2024 Sep;202(9):4125-4135
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Xu H, Song X, Zhang X, Wang G, Cheng X, Zhang L, Wang Z, Li R, Ai C, Wang X, Pu L, Chen Z, Liu W
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Chen X, Meng F, Chen C, Li S, Chou Z, Xu B, Mo JQ, Guo Y, Guan MX
The Journal of biological chemistry 2024 May;300(5):107235
The Journal of biological chemistry 2024 May;300(5):107235
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Wang J
Free radical biology & medicine 2024 Mar;214:80-86
Free radical biology & medicine 2024 Mar;214:80-86
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo.
Virga DM, Hamilton S, Osei B, Morgan A, Kneis P, Zamponi E, Park NJ, Hewitt VL, Zhang D, Gonzalez KC, Russell FM, Grahame Hardie D, Prudent J, Bloss E, Losonczy A, Polleux F, Lewis TL Jr
Nature communications 2024 Mar 8;15(1):2142
Nature communications 2024 Mar 8;15(1):2142
Inhibition of Drp1- Fis1 interaction alleviates aberrant mitochondrial fragmentation and acute kidney injury.
Song Z, Xia Y, Shi L, Zha H, Huang J, Xiang X, Li H, Huang H, Yue R, Wang H, Zhu J
Cellular & molecular biology letters 2024 Mar 4;29(1):31
Cellular & molecular biology letters 2024 Mar 4;29(1):31
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Wang W, Ma Z, Feng X, Ren J, Sun S, Shao Y, Zhang W, Yang X, Zhang J, Jing X
Arthritis research & therapy 2024 Mar 16;26(1):71
Arthritis research & therapy 2024 Mar 16;26(1):71
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
Tábara LC, Burr SP, Frison M, Chowdhury SR, Paupe V, Nie Y, Johnson M, Villar-Azpillaga J, Viegas F, Segawa M, Anand H, Petkevicius K, Chinnery PF, Prudent J
Cell 2024 Jul 11;187(14):3619-3637.e27
Cell 2024 Jul 11;187(14):3619-3637.e27
MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion.
Goldman A, Mullokandov M, Zaltsman Y, Regev L, Levin-Zaidman S, Gross A
EMBO reports 2024 Jan;25(1):45-67
EMBO reports 2024 Jan;25(1):45-67
A Mammalian Conserved Circular RNA CircLARP1B Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism.
Li J, Wang X, Shi L, Liu B, Sheng Z, Chang S, Cai X, Shan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2305902
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2305902
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Zhu Y, Huang H, Chen Z, Tao Y, Liao LY, Gao SH, Wang YJ, Gao CY
Neuroscience bulletin 2024 Feb;40(2):182-200
Neuroscience bulletin 2024 Feb;40(2):182-200
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Li Z, He R, Liu J, Jin X, Jiang B, Lao Y, Yang S
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
Rescue of mitochondrial import failure by intercellular organellar transfer.
Needs HI, Glover E, Pereira GC, Witt A, Hübner W, Dodding MP, Henley JM, Collinson I
Nature communications 2024 Feb 2;15(1):988
Nature communications 2024 Feb 2;15(1):988
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Yin H, Liu Y, Dong Q, Wang H, Yan Y, Wang X, Wan X, Yuan G, Pan Y
Cancer letters 2024 Aug 10;597:216862
Cancer letters 2024 Aug 10;597:216862
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829
Autophagy 2024 Apr;20(4):809-829
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Xiao Y, Liu X, Xie K, Luo J, Zhang Y, Huang X, Luo J, Tan S
Clinical and translational medicine 2024 Apr;14(4):e1653
Clinical and translational medicine 2024 Apr;14(4):e1653
Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity.
D'Acunzo P, Argyrousi EK, Ungania JM, Kim Y, DeRosa S, Pawlik M, Goulbourne CN, Arancio O, Levy E
Molecular neurodegeneration 2024 Apr 14;19(1):34
Molecular neurodegeneration 2024 Apr 14;19(1):34
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Tang H, Yu Q, Chen X, Zhang J, Guo D, Guo W, Zhang S, Shi X
Scientific reports 2024 Apr 12;14(1):8535
Scientific reports 2024 Apr 12;14(1):8535
Photobiomodulation provides neuroprotection through regulating mitochondrial fission imbalance in the subacute phase of spinal cord injury.
Li X, Wang XK, Zhu ZJ, Liang ZW, Li PH, Ma YG, Ding T, Li K, Zuo XS, Ju C, Zhang ZH, Song ZW, Quan HL, Zhang JW, Luo L, Wang Z, Hu XY
Neural regeneration research 2023 Sep;18(9):2005-2010
Neural regeneration research 2023 Sep;18(9):2005-2010
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Liang XL, Ouyang L, Yu NN, Sun ZH, Gui ZK, Niu YL, He QY, Zhang J, Wang Y
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose.
Yuan P, Zhang Q, Fu Y, Hou Y, Gao L, Wei Y, Feng W, Zheng X
Journal of natural medicines 2023 Mar;77(2):262-275
Journal of natural medicines 2023 Mar;77(2):262-275
Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons.
Virga DM, Hamilton S, Osei B, Morgan A, Zamponi E, Park NJ, Hewitt VL, Zhang D, Gonzalez KC, Bloss E, Polleux F, Lewis TL Jr
bioRxiv : the preprint server for biology 2023 Mar 26;
bioRxiv : the preprint server for biology 2023 Mar 26;
Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction.
Yang J, Chen P, Cao Y, Liu S, Wang W, Li L, Li J, Jiang Z, Ma Y, Chen S, Zheng S, Qi X, Jiang H
Cell chemical biology 2023 Mar 16;30(3):278-294.e11
Cell chemical biology 2023 Mar 16;30(3):278-294.e11
S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis.
Liu F, Yuan L, Li L, Yang J, Liu J, Chen Y, Zhang J, Lu Y, Yuan Y, Cheng J
Pharmacological research 2023 Jun;192:106788
Pharmacological research 2023 Jun;192:106788
Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.
Rios L, Pokhrel S, Li SJ, Heo G, Haileselassie B, Mochly-Rosen D
Nature communications 2023 Jul 19;14(1):4356
Nature communications 2023 Jul 19;14(1):4356
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Ma F, Li H, Huo H, Han Q, Liao J, Zhang H, Li Y, Pan J, Hu L, Guo J, Tang Z
Life sciences 2023 Jan 15;313:121278
Life sciences 2023 Jan 15;313:121278
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Lin S, Yang F, Hu M, Chen J, Chen G, Hu A, Li X, Fu D, Xing C, Xiong Z, Wu Y, Cao H
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins.
Muñoz-Estrada J, Nguyen AV, Goetz SC
bioRxiv : the preprint server for biology 2023 Feb 1;
bioRxiv : the preprint server for biology 2023 Feb 1;
Electroacupuncture alleviates multifidus muscle injury by modulating mitochondrial function and Ca(2+) uptake.
Li X, Zhao J, Lv Q, Tian Y, Zhang L, Liu T
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3060-3072
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3060-3072
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
Chen P, Liu W, Wei Y
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity.
Guan X, Wang Y, Li W, Liu X, Jiang J, Bian W, Xu C, Sun Y, Zhang C
Toxicology 2023 Aug 1;494:153587
Toxicology 2023 Aug 1;494:153587
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Wu Y, Yang F, Zhou G, Wang Q, Xing C, Bai H, Yi X, Xiong Z, Yang S, Cao H
Frontiers in veterinary science 2022;9:842259
Frontiers in veterinary science 2022;9:842259
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Wang P, Zhang S, Liu W, Chen S, Lv X, Hu B, Shao Z
Oxidative medicine and cellular longevity 2022;2022:7531788
Oxidative medicine and cellular longevity 2022;2022:7531788
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner.
Ferreira AR, Gouveia A, Magalhães AC, Valença I, Marques M, Kagan JC, Ribeiro D
Frontiers in cell and developmental biology 2022;10:871977
Frontiers in cell and developmental biology 2022;10:871977
AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye.
Peng F, Jiang D, Xu W, Sun Y, Zha Z, Tan X, Yu J, Pan C, Zheng Q, Chen W
Investigative ophthalmology & visual science 2022 Nov 1;63(12):18
Investigative ophthalmology & visual science 2022 Nov 1;63(12):18
Tissue Transglutaminase Knock-Out Preadipocytes and Beige Cells of Epididymal Fat Origin Possess Decreased Mitochondrial Functions Required for Thermogenesis.
Lénárt K, Bankó C, Ujlaki G, Póliska S, Kis G, Csősz É, Antal M, Bacso Z, Bai P, Fésüs L, Mádi A
International journal of molecular sciences 2022 May 5;23(9)
International journal of molecular sciences 2022 May 5;23(9)
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Hu B, Wang P, Zhang S, Liu W, Lv X, Shi D, Zhao L, Liu H, Wang B, Chen S, Shao Z
Experimental & molecular medicine 2022 Mar;54(3):309-323
Experimental & molecular medicine 2022 Mar;54(3):309-323
PINK1 regulates mitochondrial fission/fusion and neuroinflammation in β-amyloid-induced Alzheimer's disease models.
Wang X, Xue Y, Yao Y, Li Y, Ji X, Chi T, Liu P, Zou L
Neurochemistry international 2022 Mar;154:105298
Neurochemistry international 2022 Mar;154:105298
Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria.
Yang H, Sibilla C, Liu R, Yun J, Hay BA, Blackstone C, Chan DC, Harvey RJ, Guo M
Nature communications 2022 Mar 24;13(1):1582
Nature communications 2022 Mar 24;13(1):1582
Regulatory roles of external cholesterol in human airway epithelial mitochondrial function through STARD3 signalling.
Li L, Liu Y, Liu X, Zheng N, Gu Y, Song Y, Wang X
Clinical and translational medicine 2022 Jun;12(6):e902
Clinical and translational medicine 2022 Jun;12(6):e902
GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton.
Wolf C, Pouya A, Bitar S, Pfeiffer A, Bueno D, Rojas-Charry L, Arndt S, Gomez-Zepeda D, Tenzer S, Bello FD, Vianello C, Ritz S, Schwirz J, Dobrindt K, Peitz M, Hanschmann EM, Mencke P, Boussaad I, Silies M, Brüstle O, Giacomello M, Krüger R, Methner A
Communications biology 2022 Jun 3;5(1):541
Communications biology 2022 Jun 3;5(1):541
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division.
Kage F, Vicente-Manzanares M, McEwan BC, Kettenbach AN, Higgs HN
Molecular biology of the cell 2022 Jun 1;33(7):ar63
Molecular biology of the cell 2022 Jun 1;33(7):ar63
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Xiong Z, Yang F, Xu T, Yang Y, Wang F, Zhou G, Wang Q, Guo X, Xing C, Bai H, Chen J, Wu Y, Yang S, Cao H
Journal of inorganic biochemistry 2022 Jul;232:111818
Journal of inorganic biochemistry 2022 Jul;232:111818
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
Sun X, Dong S, Kato H, Kong J, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
Antioxidants (Basel, Switzerland) 2022 Jul 13;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 13;11(7)
Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy.
Cho C, Zeigler M, Mizuno S, Morrison RS, Totah RA, Barker-Haliski M
International journal of molecular sciences 2022 Jan 27;23(3)
International journal of molecular sciences 2022 Jan 27;23(3)
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1.
Waters E, Wilkinson KA, Harding AL, Carmichael RE, Robinson D, Colley HE, Guo C
EMBO reports 2022 Feb 3;23(2):e48754
EMBO reports 2022 Feb 3;23(2):e48754
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, Han Q, He H, Zhou Q
Cell death & disease 2022 Feb 16;13(2):156
Cell death & disease 2022 Feb 16;13(2):156
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, Mao X, Wu J, Xu Y, Xiong Q, Chen Z, Zhang B, Han J
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Wang L, Duan Z, Liang M, Wang C, Liang T, Sun L, Yan C, Li Q, Liang T
Chemico-biological interactions 2022 Aug 25;363:110003
Chemico-biological interactions 2022 Aug 25;363:110003
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy.
Lee A, Kondapalli C, Virga DM, Lewis TL Jr, Koo SY, Ashok A, Mairet-Coello G, Herzig S, Foretz M, Viollet B, Shaw R, Sproul A, Polleux F
Nature communications 2022 Aug 1;13(1):4444
Nature communications 2022 Aug 1;13(1):4444
Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.
Vianello C, Cocetta V, Catanzaro D, Dorn GW 2nd, De Milito A, Rizzolio F, Canzonieri V, Cecchin E, Roncato R, Toffoli G, Quagliariello V, Di Mauro A, Losito S, Maurea N, Scaffa C, Sales G, Scorrano L, Giacomello M, Montopoli M
Cell death & disease 2022 Apr 22;13(4):398
Cell death & disease 2022 Apr 22;13(4):398
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy.
Liu K, Zhao Q, Sun H, Liu L, Wang C, Li Z, Xu Y, Wang L, Zhang L, Zhang H, Chen Q, Zhao T
Cell death & disease 2022 Apr 11;13(4):334
Cell death & disease 2022 Apr 11;13(4):334
SENP3 Promotes an Mff-Primed Bcl-x (L) -Drp1 Interaction Involved in Cell Death Following Ischemia.
Guo C, Hildick KL, Jiang J, Zhao A, Guo W, Henley JM, Wilkinson KA
Frontiers in cell and developmental biology 2021;9:752260
Frontiers in cell and developmental biology 2021;9:752260
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Zhang M, Bai Y, Xu C, Qi Y, Meng J, Zhang W, Su H, Yan W
Frontiers in cell and developmental biology 2021;9:650846
Frontiers in cell and developmental biology 2021;9:650846
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Huang X, Yan Y, Zheng W, Ma Y, Wang X, Gong W, Nie S
Frontiers in cardiovascular medicine 2021;8:682409
Frontiers in cardiovascular medicine 2021;8:682409
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Ren Y, Lin Y, Chen J, Jin Y
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Biological & pharmaceutical bulletin 2021;44(10):1557-1564
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Yang DQ, Zuo QN, Wang T, Xu D, Lian L, Gao LJ, Wan C, Chen L, Wen FQ, Shen YC
Oxidative medicine and cellular longevity 2021;2021:6644238
Oxidative medicine and cellular longevity 2021;2021:6644238
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X
Nature communications 2021 Sep 6;12(1):5305
Nature communications 2021 Sep 6;12(1):5305
Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity.
Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC, Hausen AC
Nature communications 2021 Sep 2;12(1):5249
Nature communications 2021 Sep 2;12(1):5249
Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division.
Liu A, Kage F, Higgs HN
Molecular biology of the cell 2021 Oct 1;32(20):ar5
Molecular biology of the cell 2021 Oct 1;32(20):ar5
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
Xie QE, Wang MY, Cao ZP, Du X, Ji DM, Liang D, Cao YX, Liu YJ
Mitochondrion 2021 Nov;61:44-53
Mitochondrion 2021 Nov;61:44-53
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
Labbé K, Mookerjee S, Le Vasseur M, Gibbs E, Lerner C, Nunnari J
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease.
Niu M, Zhao F, Bondelid K, Siedlak SL, Torres S, Fujioka H, Wang W, Liu J, Zhu X
Aging cell 2021 May;20(5):e13347
Aging cell 2021 May;20(5):e13347
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Liu Y, Jurczak MJ, Lear TB, Lin B, Larsen MB, Kennerdell JR, Chen Y, Huckestein BR, Nguyen MK, Tuncer F, Jiang Y, Monga SP, O'Donnell CP, Finkel T, Chen BB, Mallampalli RK
Nature chemical biology 2021 Mar;17(3):298-306
Nature chemical biology 2021 Mar;17(3):298-306
Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides.
Frankowski H, Yeboah F, Berry BJ, Kinoshita C, Lee M, Evitts K, Davis J, Kinoshita Y, Morrison RS, Young JE
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway.
Hsu MC, Guo BC, Chen CH, Hu PA, Lee TS
Journal of food and drug analysis 2021 Jun 15;29(2):240-254
Journal of food and drug analysis 2021 Jun 15;29(2):240-254
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Wang LT, He PC, Li AQ, Cao KX, Yan JW, Guo S, Jiang L, Yao L, Dai XY, Feng D, Xu YM, Tan N
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Meng Q, Zaharieva EK, Sasatani M, Kobayashi J
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Redox report : communications in free radical research 2021 Dec;26(1):160-169
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
König T, Nolte H, Aaltonen MJ, Tatsuta T, Krols M, Stroh T, Langer T, McBride HM
Nature cell biology 2021 Dec;23(12):1271-1286
Nature cell biology 2021 Dec;23(12):1271-1286
Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson's disease-associated phenotypes in vivo.
Hang L, Wang Z, Foo ASC, Goh GWY, Choong HC, Thundyil J, Xu S, Lam KP, Lim KL
Neurobiology of disease 2021 Dec;161:105560
Neurobiology of disease 2021 Dec;161:105560
The XBP1‒MARCH5‒MFN2 Axis Confers Endoplasmic Reticulum Stress Resistance by Coordinating Mitochondrial Fission and Mitophagy in Melanoma.
Wang H, Yi X, Guo S, Wang S, Ma J, Zhao T, Shi Q, Tian Y, Wang H, Jia L, Gao T, Li C, Guo W
The Journal of investigative dermatology 2021 Dec;141(12):2932-2943.e12
The Journal of investigative dermatology 2021 Dec;141(12):2932-2943.e12
Diethyl Succinate Modulates Microglial Polarization and Activation by Reducing Mitochondrial Fission and Cellular ROS.
Wang L, Zhang Y, Kiprowska M, Guo Y, Yamamoto K, Li X
Metabolites 2021 Dec 8;11(12)
Metabolites 2021 Dec 8;11(12)
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
Jin C, Xue W, Liu Q, Han J, Luo R, Feng J, Liu J, Guo T, Peng X, Hu T
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy.
Hung CM, Lombardo PS, Malik N, Brun SN, Hellberg K, Van Nostrand JL, Garcia D, Baumgart J, Diffenderfer K, Asara JM, Shaw RJ
Science advances 2021 Apr;7(15)
Science advances 2021 Apr;7(15)
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Kong XT, Wang Z, Mou JJ, Li CS, Xue HL, Wu M, Chen L, Xu JH, Xu LX
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
Feng X, Wang S, Yang X, Lin J, Man W, Dong Y, Zhang Y, Zhao Z, Wang H, Sun D
Frontiers in cell and developmental biology 2020;8:628842
Frontiers in cell and developmental biology 2020;8:628842
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Wang Z, Xu JH, Mou JJ, Kong XT, Wu M, Xue HL, Xu LX
Frontiers in physiology 2020;11:408
Frontiers in physiology 2020;11:408
Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation.
Fei M, Zhang L, Wang H, Zhu Y, Niu W, Tang T, Han Y
Frontiers in oncology 2020;10:516746
Frontiers in oncology 2020;10:516746
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
Moyzis AG, Lally NS, Liang W, Leon LJ, Najor RH, Orogo AM, Gustafsson ÅB
Journal of molecular and cellular cardiology 2020 Sep;146:109-120
Journal of molecular and cellular cardiology 2020 Sep;146:109-120
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Guo L, Cui C, Wang J, Yuan J, Yang Q, Zhang P, Su W, Bao R, Ran J, Wu C
Nature communications 2020 Oct 1;11(1):4913
Nature communications 2020 Oct 1;11(1):4913
Novel ultrastructural findings on cardiac mitochondria of huddling Brandt's voles in mild cold environment.
Wang Z, Xu JH, Mou JJ, Kong XT, Zou JW, Xue HL, Wu M, Xu LX
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2020 Nov;249:110766
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2020 Nov;249:110766
Protein Kinase C-δ Mediates Kidney Tubular Injury in Cold Storage-Associated Kidney Transplantation.
Zhu J, Zhang G, Song Z, Xiang X, Shu S, Liu Z, Yang D, Wei Q, Dong Z
Journal of the American Society of Nephrology : JASN 2020 May;31(5):1050-1065
Journal of the American Society of Nephrology : JASN 2020 May;31(5):1050-1065
Morphometric, Hemodynamic, and Multi-Omics Analyses in Heart Failure Rats with Preserved Ejection Fraction.
Zhang W, Zhang H, Yao W, Li L, Niu P, Huo Y, Tan W
International journal of molecular sciences 2020 May 9;21(9)
International journal of molecular sciences 2020 May 9;21(9)
Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet.
Ahn Y, Sabouny R, Villa BR, Yee NC, Mychasiuk R, Uddin GM, Rho JM, Shutt TE
International journal of molecular sciences 2020 May 5;21(9)
International journal of molecular sciences 2020 May 5;21(9)
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
Nagashima S, Tábara LC, Tilokani L, Paupe V, Anand H, Pogson JH, Zunino R, McBride HM, Prudent J
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.
Tokuyama T, Hirai A, Shiiba I, Ito N, Matsuno K, Takeda K, Saito K, Mii K, Matsushita N, Fukuda T, Inatome R, Yanagi S
Biomolecules 2020 Mar 13;10(3)
Biomolecules 2020 Mar 13;10(3)
Drp1/Mff signaling pathway is involved in fluoride-induced abnormal fission of hepatocyte mitochondria in mice.
Zhou BH, Wei SS, Jia LS, Zhang Y, Miao CY, Wang HW
The Science of the total environment 2020 Jul 10;725:138192
The Science of the total environment 2020 Jul 10;725:138192
Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer.
Lee YG, Nam Y, Shin KJ, Yoon S, Park WS, Joung JY, Seo JK, Jang J, Lee S, Nam D, Caino MC, Suh PG, Chan Chae Y
Cancer letters 2020 Feb 28;471:72-87
Cancer letters 2020 Feb 28;471:72-87
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Guo J, Ren R, Yao X, Ye Y, Sun K, Lin J, Wang G, Guo F, Xiao J, Xu T
Aging 2020 Feb 25;12(4):3976-3992
Aging 2020 Feb 25;12(4):3976-3992
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.
Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, Chan ER, Wang Q, Xu R, Flanagan ME, Pieper AA, Qi X
Science advances 2020 Dec;6(49)
Science advances 2020 Dec;6(49)
Desferoxamine protects against glucocorticoid-induced osteonecrosis of the femoral head via activating HIF-1α expression.
Jing X, Du T, Yang X, Zhang W, Wang G, Liu X, Li T, Jiang Z
Journal of cellular physiology 2020 Dec;235(12):9864-9875
Journal of cellular physiology 2020 Dec;235(12):9864-9875
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
Dasgupta A, Chen KH, Wu D, Hoskin V, Mewburn J, Lima PDA, Parlow LRG, Hindmarch CCT, Martin A, Sykes EA, Tayade C, Lightbody ED, Madarnas Y, SenGupta SK, Elliott BE, Nicol CJB, Archer SL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5106-5127
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5106-5127
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Zeng Y, Pan Q, Wang X, Li D, Lin Y, Man F, Xiao F, Guo L
Oxidative medicine and cellular longevity 2019;2019:4508762
Oxidative medicine and cellular longevity 2019;2019:4508762
Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer.
Seo JH, Agarwal E, Chae YC, Lee YG, Garlick DS, Storaci AM, Ferrero S, Gaudioso G, Gianelli U, Vaira V, Altieri DC
EBioMedicine 2019 Oct;48:353-363
EBioMedicine 2019 Oct;48:353-363
Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.
Heo JM, Harper NJ, Paulo JA, Li M, Xu Q, Coughlin M, Elledge SJ, Harper JW
Science advances 2019 Nov;5(11):eaay4624
Science advances 2019 Nov;5(11):eaay4624
Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway.
Tanaka H, Okazaki T, Aoyama S, Yokota M, Koike M, Okada Y, Fujiki Y, Gotoh Y
Journal of cell science 2019 May 31;132(11)
Journal of cell science 2019 May 31;132(11)
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC
Cell 2019 May 30;177(6):1536-1552.e23
Cell 2019 May 30;177(6):1536-1552.e23
Neuronal susceptibility to beta-amyloid toxicity and ischemic injury involves histone deacetylase-2 regulation of endophilin-B1.
Wang DB, Kinoshita C, Kinoshita Y, Sopher BL, Uo T, Lee RJ, Kim JK, Murphy SP, Dirk Keene C, Garden GA, Morrison RS
Brain pathology (Zurich, Switzerland) 2019 Mar;29(2):164-175
Brain pathology (Zurich, Switzerland) 2019 Mar;29(2):164-175
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Zhao Y, Sun X, Hu D, Prosdocimo DA, Hoppel C, Jain MK, Ramachandran R, Qi X
Nature communications 2019 Mar 26;10(1):1371
Nature communications 2019 Mar 26;10(1):1371
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis.
Yedida G, Milani M, Cohen GM, Varadarajan S
Cell death & disease 2019 Jul 8;10(7):521
Cell death & disease 2019 Jul 8;10(7):521
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T
EMBO molecular medicine 2019 Jan;11(1)
EMBO molecular medicine 2019 Jan;11(1)
Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.
Chen CW, Wang HL, Huang CW, Huang CY, Lim WK, Tu IC, Koorapati A, Hsieh ST, Kan HW, Tzeng SR, Liao JC, Chong WM, Naroditzky I, Kidron D, Eran A, Nijim Y, Sela E, Feldman HB, Kalfon L, Raveh-Barak H, Falik-Zaccai TC, Elpeleg O, Mandel H, Chang ZF
Proceedings of the National Academy of Sciences of the United States of America 2019 Jan 8;116(2):566-574
Proceedings of the National Academy of Sciences of the United States of America 2019 Jan 8;116(2):566-574
Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity.
Rangaraju V, Lauterbach M, Schuman EM
Cell 2019 Jan 10;176(1-2):73-84.e15
Cell 2019 Jan 10;176(1-2):73-84.e15
Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior.
Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, Matsumoto H, Miyakawa T, Nakada K
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Feb 27;39(9):1588-1604
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Feb 27;39(9):1588-1604
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.
D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J
Molecular cell 2019 Feb 21;73(4):775-787.e10
Molecular cell 2019 Feb 21;73(4):775-787.e10
Quantifying the inhibitory effect of Bcl-xl on the action of Mff using live-cell fluorescence imaging.
Ma Y, Du M, Yang F, Mai Z, Zhang C, Qu W, Wang B, Wang X, Chen T
FEBS open bio 2019 Dec;9(12):2041-2051
FEBS open bio 2019 Dec;9(12):2041-2051
MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer.
Seo JH, Chae YC, Kossenkov AV, Lee YG, Tang HY, Agarwal E, Gabrilovich DI, Languino LR, Speicher DW, Shastrula PK, Storaci AM, Ferrero S, Gaudioso G, Caroli M, Tosi D, Giroda M, Vaira V, Rebecca VW, Herlyn M, Xiao M, Fingerman D, Martorella A, Skordalakes E, Altieri DC
Cancer research 2019 Dec 15;79(24):6215-6226
Cancer research 2019 Dec 15;79(24):6215-6226
Novel findings on ultrastructural protection of skeletal muscle fibers during hibernation of Daurian ground squirrels: Mitochondria, nuclei, cytoskeleton, glycogen.
Wang Z, Jiang SF, Cao J, Liu K, Xu SH, Arfat Y, Guo QL, Chang H, Goswami N, Hinghofer-Szalkay H, Gao YF
Journal of cellular physiology 2019 Aug;234(8):13318-13331
Journal of cellular physiology 2019 Aug;234(8):13318-13331
MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress.
Nagashima S, Takeda K, Ohno N, Ishido S, Aoki M, Saitoh Y, Takada T, Tokuyama T, Sugiura A, Fukuda T, Matsushita N, Inatome R, Yanagi S
Life science alliance 2019 Aug;2(4)
Life science alliance 2019 Aug;2(4)
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, Lu K, Yan R, Zhang Y, Pan X, Zhao X, Li W, Zhang H, Zhou Q, Gao P
Cell metabolism 2019 Apr 2;29(4):979-992.e4
Cell metabolism 2019 Apr 2;29(4):979-992.e4
Clinical and Biochemical Features in a Patient With Mitochondrial Fission Factor Gene Alteration.
Nasca A, Nardecchia F, Commone A, Semeraro M, Legati A, Garavaglia B, Ghezzi D, Leuzzi V
Frontiers in genetics 2018;9:625
Frontiers in genetics 2018;9:625
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Lin HH, Chung Y, Cheng CT, Ouyang C, Fu Y, Kuo CY, Chi KK, Sadeghi M, Chu P, Kung HJ, Li CF, Limesand KH, Ann DK
Autophagy 2018;14(9):1481-1498
Autophagy 2018;14(9):1481-1498
Polybrene induces neural degeneration by bidirectional Ca(2+) influx-dependent mitochondrial and ER-mitochondrial dynamics.
Bao F, Shi H, Gao M, Yang L, Zhou L, Zhao Q, Wu Y, Chen K, Xiang G, Long Q, Guo J, Zhang J, Liu X
Cell death & disease 2018 Sep 20;9(10):966
Cell death & disease 2018 Sep 20;9(10):966
A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission.
Lee J, Pappalardo Z, Chopra DG, Hennings TG, Vaughn I, Lan C, Choe JJ, Ang K, Chen S, Arkin M, McManus MT, German MS, Ku GM
Endocrinology 2018 Sep 1;159(9):3321-3330
Endocrinology 2018 Sep 1;159(9):3321-3330
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM
Endocrinology 2018 Sep 1;159(9):3245-3256
Endocrinology 2018 Sep 1;159(9):3245-3256
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, Chen S, Shi A, Chan DC, Song Z
Cell reports 2018 Jun 5;23(10):2989-3005
Cell reports 2018 Jun 5;23(10):2989-3005
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.
Chakrabarti R, Ji WK, Stan RV, de Juan Sanz J, Ryan TA, Higgs HN
The Journal of cell biology 2018 Jan 2;217(1):251-268
The Journal of cell biology 2018 Jan 2;217(1):251-268
TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue.
Velazquez-Villegas LA, Perino A, Lemos V, Zietak M, Nomura M, Pols TWH, Schoonjans K
Nature communications 2018 Jan 16;9(1):245
Nature communications 2018 Jan 16;9(1):245
Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network.
Liu X, Wang W, Song G, Wei X, Zeng Y, Han P, Wang D, Shao M, Wu J, Sun H, Xiong G, Li S
PloS one 2017;12(8):e0182558
PloS one 2017;12(8):e0182558
Mitochondria elongation is mediated through SIRT1-mediated MFN1 stabilization.
Oanh NTK, Park YY, Cho H
Cellular signalling 2017 Oct;38:67-75
Cellular signalling 2017 Oct;38:67-75
Mechanical force induces mitochondrial fission.
Helle SCJ, Feng Q, Aebersold MJ, Hirt L, Grüter RR, Vahid A, Sirianni A, Mostowy S, Snedeker JG, Šarić A, Idema T, Zambelli T, Kornmann B
eLife 2017 Nov 9;6
eLife 2017 Nov 9;6
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death.
Guo C, Wilkinson KA, Evans AJ, Rubin PP, Henley JM
Scientific reports 2017 Mar 6;7:43811
Scientific reports 2017 Mar 6;7:43811
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease.
Zhao F, Wang W, Wang C, Siedlak SL, Fujioka H, Tang B, Zhu X
Biochimica et biophysica acta. Molecular basis of disease 2017 Jun;1863(6):1359-1370
Biochimica et biophysica acta. Molecular basis of disease 2017 Jun;1863(6):1359-1370
Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin.
Ban T, Ishihara T, Kohno H, Saita S, Ichimura A, Maenaka K, Oka T, Mihara K, Ishihara N
Nature cell biology 2017 Jul;19(7):856-863
Nature cell biology 2017 Jul;19(7):856-863
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum.
Ji WK, Chakrabarti R, Fan X, Schoenfeld L, Strack S, Higgs HN
The Journal of cell biology 2017 Dec 4;216(12):4123-4139
The Journal of cell biology 2017 Dec 4;216(12):4123-4139
The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1.
Sabouny R, Fraunberger E, Geoffrion M, Ng AC, Baird SD, Screaton RA, Milne R, McBride HM, Shutt TE
Antioxidants & redox signaling 2017 Dec 20;27(18):1447-1459
Antioxidants & redox signaling 2017 Dec 20;27(18):1447-1459
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Xu Z, Jin X, Pan T, Liu T, Wan N, Li S
Oncotarget 2017 Aug 8;8(32):52629-52641
Oncotarget 2017 Aug 8;8(32):52629-52641
N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics.
Casinelli G, LaRosa J, Sharma M, Cherok E, Banerjee S, Branca M, Edmunds L, Wang Y, Sims-Lucas S, Churley L, Kelly S, Sun M, Stolz D, Graves JA
Cell death discovery 2016;2:16082
Cell death discovery 2016;2:16082
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes.
Jugé R, Breugnot J, Da Silva C, Bordes S, Closs B, Aouacheria A
Scientific reports 2016 Oct 12;6:35065
Scientific reports 2016 Oct 12;6:35065
SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells.
Liu S, Gao Y, Zhang C, Li H, Pan S, Wang X, Du S, Deng Z, Wang L, Song Z, Chen S
FEBS letters 2016 May;590(9):1313-23
FEBS letters 2016 May;590(9):1313-23
Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission.
Saita S, Ishihara T, Maeda M, Iemura S, Natsume T, Mihara K, Ishihara N
Genes to cells : devoted to molecular & cellular mechanisms 2016 May;21(5):408-24
Genes to cells : devoted to molecular & cellular mechanisms 2016 May;21(5):408-24
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z
Cell death and differentiation 2016 Mar;23(3):380-92
Cell death and differentiation 2016 Mar;23(3):380-92
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Wu W, Lin C, Wu K, Jiang L, Wang X, Li W, Zhuang H, Zhang X, Chen H, Li S, Yang Y, Lu Y, Wang J, Zhu R, Zhang L, Sui S, Tan N, Zhao B, Zhang J, Li L, Feng D
The EMBO journal 2016 Jul 1;35(13):1368-84
The EMBO journal 2016 Jul 1;35(13):1368-84
Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis.
Zhang Z, Liu L, Wu S, Xing D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Jan;30(1):466-76
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Jan;30(1):466-76
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
Korwitz A, Merkwirth C, Richter-Dennerlein R, Tröder SE, Sprenger HG, Quirós PM, López-Otín C, Rugarli EI, Langer T
The Journal of cell biology 2016 Jan 18;212(2):157-66
The Journal of cell biology 2016 Jan 18;212(2):157-66
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein.
Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, Polster BM, Boyman L, Lederer WJ, Wang C, Karbowski M
Molecular biology of the cell 2016 Jan 15;27(2):349-59
Molecular biology of the cell 2016 Jan 15;27(2):349-59
Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling.
Otera H, Miyata N, Kuge O, Mihara K
The Journal of cell biology 2016 Feb 29;212(5):531-44
The Journal of cell biology 2016 Feb 29;212(5):531-44
Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin.
Kulkarni SS, Joffraud M, Boutant M, Ratajczak J, Gao AW, Maclachlan C, Hernandez-Alvarez MI, Raymond F, Metairon S, Descombes P, Houtkooper RH, Zorzano A, Cantó C
Diabetes 2016 Dec;65(12):3552-3560
Diabetes 2016 Dec;65(12):3552-3560
Correcting mitochondrial fusion by manipulating mitofusin conformations.
Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II
Nature 2016 Dec 1;540(7631):74-79
Nature 2016 Dec 1;540(7631):74-79
Multiple dynamin family members collaborate to drive mitochondrial division.
Lee JE, Westrate LM, Wu H, Page C, Voeltz GK
Nature 2016 Dec 1;540(7631):139-143
Nature 2016 Dec 1;540(7631):139-143
Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function.
Bal NC, Maurya SK, Singh S, Wehrens XH, Periasamy M
The Journal of biological chemistry 2016 Aug 12;291(33):17247-57
The Journal of biological chemistry 2016 Aug 12;291(33):17247-57
COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1.
Ban-Ishihara R, Tomohiro-Takamiya S, Tani M, Baudier J, Ishihara N, Kuge O
FEBS letters 2015 Oct 7;589(20 Pt B):3126-32
FEBS letters 2015 Oct 7;589(20 Pt B):3126-32
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate.
Ducommun S, Deak M, Sumpton D, Ford RJ, Núñez Galindo A, Kussmann M, Viollet B, Steinberg GR, Foretz M, Dayon L, Morrice NA, Sakamoto K
Cellular signalling 2015 May;27(5):978-88
Cellular signalling 2015 May;27(5):978-88
Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.
Gao J, Qin S, Jiang C
Acta biochimica et biophysica Sinica 2015 Jul;47(7):522-9
Acta biochimica et biophysica Sinica 2015 Jul;47(7):522-9
Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N
Molecular and cellular biology 2015 Jan;35(1):211-23
Molecular and cellular biology 2015 Jan;35(1):211-23
Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission.
Li S, Xu S, Roelofs BA, Boyman L, Lederer WJ, Sesaki H, Karbowski M
The Journal of cell biology 2015 Jan 5;208(1):109-23
The Journal of cell biology 2015 Jan 5;208(1):109-23
AKAP350C targets to mitochondria via a novel amphipathic alpha helical domain.
Mason TA, Goldenring JR, Kolobova E
Cellular logistics 2014 Jul-Sep;4(3):e943597
Cellular logistics 2014 Jul-Sep;4(3):e943597
Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons.
Wang DB, Uo T, Kinoshita C, Sopher BL, Lee RJ, Murphy SP, Kinoshita Y, Garden GA, Wang HG, Morrison RS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Feb 12;34(7):2674-83
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Feb 12;34(7):2674-83
Loss of Yme1L perturbates mitochondrial dynamics.
Ruan Y, Li H, Zhang K, Jian F, Tang J, Song Z
Cell death & disease 2013 Oct 31;4(10):e896
Cell death & disease 2013 Oct 31;4(10):e896
Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c.
Ban-Ishihara R, Ishihara T, Sasaki N, Mihara K, Ishihara N
Proceedings of the National Academy of Sciences of the United States of America 2013 Jul 16;110(29):11863-8
Proceedings of the National Academy of Sciences of the United States of America 2013 Jul 16;110(29):11863-8
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Qi X, Qvit N, Su YC, Mochly-Rosen D
Journal of cell science 2013 Feb 1;126(Pt 3):789-802
Journal of cell science 2013 Feb 1;126(Pt 3):789-802
ER tubules mark sites of mitochondrial division.
Friedman JR, Lackner LL, West M, DiBenedetto JR, Nunnari J, Voeltz GK
Science (New York, N.Y.) 2011 Oct 21;334(6054):358-62
Science (New York, N.Y.) 2011 Oct 21;334(6054):358-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 17090-1-AP(MFF antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using MFF antibody 17090-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MFF (IP:17090-1-AP, 3ug; Detection:17090-1-AP 1:1000) with mouse brain tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17090-1-AP(MFF antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17090-1-AP(MFF antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
