Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14340-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14340-1-AP, RRID:AB_2158774
- Product name
- PALB2 antibody
- Antibody type
- Polyclonal
- Description
- PALB2 antibody (Cat. #14340-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Erbin destabilization by O-GlcNAcylation promotes 5-FU resistance via homologous recombination activation in colorectal cancer.
Prognostic value and experimental validation of atherosclerosis-derived pathogenic genes in colorectal cancer.
Intranuclear paraspeckle-circular RNA TACC3 assembly forms RNA-DNA hybrids to facilitate MASH-related hepatocellular carcinoma growth in an m(6)A-dependent manner.
Arginine methylation-dependent METTL14-SMN interaction regulates RNA m(6)A homeostasis.
ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination.
KLC3 activates PI3K/AKT signaling and promotes ovarian cancer cell proliferation and migration through COL3A1.
Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma.
The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells.
Haploinsufficiency of ZNF251 causes DNA-PKcs-dependent resistance to PARP inhibitors in BRCA1-mutated cancer cells.
FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50.
m(6) A deposition is regulated by PRMT1-mediated arginine methylation of METTL14 in its disordered C-terminal region.
Zhang J, Liu C, Tang Y, Gao K, Xu W, Zhang J, Zhao L, Wang G
Biochemical pharmacology 2026 Jan;243(Pt 1):117400
Biochemical pharmacology 2026 Jan;243(Pt 1):117400
Prognostic value and experimental validation of atherosclerosis-derived pathogenic genes in colorectal cancer.
Li Y, Wei J, Xu Y, Wu Z, He S, Zhu Y, Ni W, Zhang D, Xu H, Zhang C, Zhou A, Shen T, Li J
Frontiers in oncology 2025;15:1728087
Frontiers in oncology 2025;15:1728087
Intranuclear paraspeckle-circular RNA TACC3 assembly forms RNA-DNA hybrids to facilitate MASH-related hepatocellular carcinoma growth in an m(6)A-dependent manner.
Fu J, Wei Y, Yang Y, Yang X, Ouyang T, Wang X, Chen S, Liu Z, Su Y, Fu J, Yu M, Qian H, Song H, Xu S, Zhao R, Jiang X, Huo Y, Zhang M, Yang P, Yang Z, Wang K, Li L, Wang H
Cancer communications (London, England) 2025 Nov;45(11):1583-1610
Cancer communications (London, England) 2025 Nov;45(11):1583-1610
Arginine methylation-dependent METTL14-SMN interaction regulates RNA m(6)A homeostasis.
Zhang Y, Shen L, Ren L, Wei J, Pham HQH, Tao X, Guo J, Wang Z, Shen B, Su R, He C, Yang Y
EMBO reports 2025 Nov;26(22):5483-5500
EMBO reports 2025 Nov;26(22):5483-5500
ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination.
Li H, Chatla S, Liu X, Tian Z, Vekariya U, Wang P, Kim D, Octaviani S, Lian Z, Morton G, Feng Z, Yang D, Sullivan-Reed K, Childers W, Yu X, Chitrala KN, Madzo J, Skorski T, Huang J
Cancer letters 2025 Mar 31;613:217505
Cancer letters 2025 Mar 31;613:217505
KLC3 activates PI3K/AKT signaling and promotes ovarian cancer cell proliferation and migration through COL3A1.
Yang J, He R, Zhang X, Wang X, Liu M, Liu X, Li Y
Oncology reports 2025 Jun;53(6)
Oncology reports 2025 Jun;53(6)
Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma.
Wang SW, Hong WF, Huang YL, Zheng YM, Zheng QY, Cheng JJ, Tang BF, Chen GW, Liang BG, Lu JC, Yuan L, Hsu SJ, Zhang Y, Zheng XB, Zeng ZC, Zhou J, Fan J, Ke AW, Gao C, Du SS
Cellular & molecular immunology 2025 Dec;22(12):1549-1566
Cellular & molecular immunology 2025 Dec;22(12):1549-1566
The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells.
Li Y, Wang X, Liu X, Li X, Zhang J, Li Y
PloS one 2024;19(12):e0316476
PloS one 2024;19(12):e0316476
Haploinsufficiency of ZNF251 causes DNA-PKcs-dependent resistance to PARP inhibitors in BRCA1-mutated cancer cells.
Li H, Chatla S, Liu X, Vekariya U, Kim D, Walt M, Lian Z, Morton G, Feng Z, Yang D, Liu H, Reed K, Childers W, Yu X, Madzo J, Chitrala KN, Skorski T, Huang J
Research square 2023 Apr 6;
Research square 2023 Apr 6;
FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50.
Inci G, Warkad MS, Kang BG, Lee NK, Suh HW, Lim SS, Kim J, Kim SC, Lee JY
Molecules (Basel, Switzerland) 2022 Dec 6;27(23)
Molecules (Basel, Switzerland) 2022 Dec 6;27(23)
m(6) A deposition is regulated by PRMT1-mediated arginine methylation of METTL14 in its disordered C-terminal region.
Wang Z, Pan Z, Adhikari S, Harada BT, Shen L, Yuan W, Abeywardana T, Al-Hadid Q, Stark JM, He C, Lin L, Yang Y
The EMBO journal 2021 Mar 1;40(5):e106309
The EMBO journal 2021 Mar 1;40(5):e106309
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PALB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PALB2. This antibody recognizes human,mouse,rat antigen. The PALB2 antibody has been validated for the following applications: ELISA, WB analysis.