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- References [23]
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- Immunohistochemistry [1]
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- Product number
- 11275-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11275-1-AP, RRID:AB_10640533
- Product name
- CREB3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CREB3 antibody (Cat. #11275-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Heme oxygenase-1 attenuates sepsis-associated acute lung injury by suppressing the CREB3/ARF4 signaling pathway to mitigate Golgi stress in macrophages.
CREB3 gain of function variants protect against ALS.
Establishment of immortalized porcine intramuscular preadipocytes for the study of lipid metabolism.
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
MUC1 and CREB3 are Hub Ferroptosis Suppressors for Nucleus Pulposus and Annulus Fibrosus Degeneration by Integrated Bioinformatics and Experimental Verification.
Small Leucine Zipper Protein Regulates Glucose Metabolism of Prostate Cancer Cells via Induction of Phosphoglycerate Kinase 1.
Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death.
CREB3 facilitates Donafenib resistance in hepatocellular carcinoma cells via the LSD1/CoREST/p65 axis by transcriptionally activating long noncoding RNA ZFAS1.
CREB3 mediates the transcriptional regulation of PGC-1α, a master regulator of energy homeostasis and mitochondrial biogenesis.
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
Small leucine zipper protein functions as a modulator for metabolic reprogramming of colorectal cancer cells by inducing nutrient stress-mediated autophagy.
miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC.
Expression analysis and functional characterization of thioredoxin domain-containing protein 11.
CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells.
Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation.
Elucidation of brefeldin A-induced ER and Golgi stress responses in Neuro2a cells.
Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells.
Molecular characterization of mouse CREB3 regulatory factor in Neuro2a cells.
Small leucine zipper protein promotes the metastasis of castration-resistant prostate cancer through transcriptional regulation of matrix metalloproteinase-13.
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing.
Regulation of the ER-bound transcription factor Luman/CREB3 in HEK293 cells.
LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.
JAB1/CSN5 inhibits the activity of Luman/CREB3 by promoting its degradation.
Kong C, Zhang Y, Li X, Ren G, Guo C, Li M, Liu W, Zhang D, Li C, Shi J, Gong L, Yu J
Free radical biology & medicine 2026 Apr 10;251:91-107
Free radical biology & medicine 2026 Apr 10;251:91-107
CREB3 gain of function variants protect against ALS.
Megat S, Marques C, Hernán-Godoy M, Sellier C, Stuart-Lopez G, Dirrig-Grosch S, Gorin C, Brunet A, Fischer M, Keime C, Kessler P, Mendoza-Parra MA, Zwamborn RAJ, Veldink JH, Scholz SW, Ferrucci L, Ludolph A, Traynor B, Chio A, Dupuis L, Rouaux C
Nature communications 2025 Mar 26;16(1):2942
Nature communications 2025 Mar 26;16(1):2942
Establishment of immortalized porcine intramuscular preadipocytes for the study of lipid metabolism.
Locke B, Lu R
Biochemistry and cell biology = Biochimie et biologie cellulaire 2025 Jan 1;103:1-11
Biochemistry and cell biology = Biochimie et biologie cellulaire 2025 Jan 1;103:1-11
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Gao Y, Zhu J, Xin H, Ni B, Liu Z
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
MUC1 and CREB3 are Hub Ferroptosis Suppressors for Nucleus Pulposus and Annulus Fibrosus Degeneration by Integrated Bioinformatics and Experimental Verification.
Yang X, Li Q, Wang L, Chen J, Quan Z
Journal of inflammation research 2024;17:8965-8984
Journal of inflammation research 2024;17:8965-8984
Small Leucine Zipper Protein Regulates Glucose Metabolism of Prostate Cancer Cells via Induction of Phosphoglycerate Kinase 1.
Han S, Park S, Kim S, Kwon S, Ko J
Cancers 2024 Nov 18;16(22)
Cancers 2024 Nov 18;16(22)
Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death.
Lee GE, Bang G, Byun J, Lee CJ, Chen W, Jeung D, An HJ, Kang HC, Lee JY, Lee HS, Hong YS, Kim DJ, Keniry M, Kim JY, Choi JS, Fanto M, Cho SJ, Kim KD, Cho YY
Experimental & molecular medicine 2024 Mar;56(3):686-699
Experimental & molecular medicine 2024 Mar;56(3):686-699
CREB3 facilitates Donafenib resistance in hepatocellular carcinoma cells via the LSD1/CoREST/p65 axis by transcriptionally activating long noncoding RNA ZFAS1.
Hou X, Xu Q, Liu R
Translational oncology 2024 Jun;44:101684
Translational oncology 2024 Jun;44:101684
CREB3 mediates the transcriptional regulation of PGC-1α, a master regulator of energy homeostasis and mitochondrial biogenesis.
Locke B, Campbell E, Lu R
FEBS letters 2024 Jul;598(14):1730-1739
FEBS letters 2024 Jul;598(14):1730-1739
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
Oh-Hashi K, Nakamura H, Ogawa H, Hirata Y, Sakurai K
International journal of molecular sciences 2023 Mar 17;24(6)
International journal of molecular sciences 2023 Mar 17;24(6)
Small leucine zipper protein functions as a modulator for metabolic reprogramming of colorectal cancer cells by inducing nutrient stress-mediated autophagy.
Kim S, Oh M, Kang M, Ko J
Cellular and molecular life sciences : CMLS 2022 Sep 4;79(9):505
Cellular and molecular life sciences : CMLS 2022 Sep 4;79(9):505
miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC.
Shibata T, Cao DY, Dar TB, Ahmed F, Bhat SA, Veiras LC, Bernstein EA, Khan AA, Chaum M, Shiao SL, Tourtellotte WG, Giani JF, Bernstein KE, Cui X, Vail E, Khan Z
Cancers 2022 Oct 27;14(21)
Cancers 2022 Oct 27;14(21)
Expression analysis and functional characterization of thioredoxin domain-containing protein 11.
Murase R, Yamamoto A, Hirata Y, Oh-Hashi K
Molecular biology reports 2022 Nov;49(11):10541-10556
Molecular biology reports 2022 Nov;49(11):10541-10556
CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells.
Yadavalli T, Sharma P, Wu D, Kapoor D, Shukla D
Viruses 2022 May 28;14(6)
Viruses 2022 May 28;14(6)
Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation.
Wang M, Zhang Y, Komaniecki GP, Lu X, Cao J, Zhang M, Yu T, Hou D, Spiegelman NA, Yang M, Price IR, Lin H
Nature communications 2022 Aug 2;13(1):4494
Nature communications 2022 Aug 2;13(1):4494
Elucidation of brefeldin A-induced ER and Golgi stress responses in Neuro2a cells.
Oh-Hashi K, Hasegawa T, Mizutani Y, Takahashi K, Hirata Y
Molecular and cellular biochemistry 2021 Oct;476(10):3869-3877
Molecular and cellular biochemistry 2021 Oct;476(10):3869-3877
Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells.
Oh-Hashi K, Yamamoto A, Murase R, Hirata Y
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Molecular characterization of mouse CREB3 regulatory factor in Neuro2a cells.
Oh-Hashi K, Hasegawa T, Naruse Y, Hirata Y
Molecular biology reports 2021 Jul;48(7):5411-5420
Molecular biology reports 2021 Jul;48(7):5411-5420
Small leucine zipper protein promotes the metastasis of castration-resistant prostate cancer through transcriptional regulation of matrix metalloproteinase-13.
Kim S, Kang M, Ko J
Carcinogenesis 2021 Aug 19;42(8):1089-1099
Carcinogenesis 2021 Aug 19;42(8):1089-1099
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing.
Yadavalli T, Suryawanshi R, Koganti R, Hopkins J, Ames J, Koujah L, Iqbal A, Madavaraju K, Agelidis A, Shukla D
Science advances 2020 Dec;6(49)
Science advances 2020 Dec;6(49)
Regulation of the ER-bound transcription factor Luman/CREB3 in HEK293 cells.
Oh-Hashi K, Takahashi K, Hirata Y
FEBS letters 2019 Oct;593(19):2771-2778
FEBS letters 2019 Oct;593(19):2771-2778
LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.
Penney J, Taylor T, MacLusky N, Lu R
Frontiers in molecular neuroscience 2018;11:352
Frontiers in molecular neuroscience 2018;11:352
JAB1/CSN5 inhibits the activity of Luman/CREB3 by promoting its degradation.
DenBoer LM, Iyer A, McCluggage AR, Li Y, Martyn AC, Lu R
Biochimica et biophysica acta 2013 Sep;1829(9):921-9
Biochimica et biophysica acta 2013 Sep;1829(9):921-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 11275-1-AP(CREB3 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CREB3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CREB3. This antibody recognizes human antigen. The CREB3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
