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Western blot
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- Antibody Data
- Antigen structure
- References [1]
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- Other assay [1]
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- Product number
- PA5-100892 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CYP7A1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Antibody detects endogenous levels of total Cytochrome P450 7A1.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- -20°C
Submitted references Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice.
Nyandwi JB, Ko YS, Jin H, Yun SP, Park SW, Kim HJ
Biomolecules 2021 Oct 6;11(10)
Biomolecules 2021 Oct 6;11(10)
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 4 RA significantly induces ABCG5/8 and ABCA1 protein levels, which are involved in hepatobilial cholesterol excretion, and CYP7A1 protein levels, a key rate-limiting enzyme for bile acid biosynthesis in HFD-fed mice. ( A - D ) ABCG5, ABCG8, ABCA1, and ( E , F ) CYP7A1 protein levels were examined in liver tissues by western blot analysis, and the relative protein levels are presented as the mean +- SD ( n = 4-6). ** p < 0.01 vs. ND control mice; # p < 0.05, ## p < 0.01, vs. HFD mice; $ p < 0.05, $$ p < 0.01 vs. RA 50.
