Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 18895-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18895-1-AP, RRID:AB_10597385
- Product name
- LAPTM4B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LAPTM4B antibody (Cat. #18895-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrative Genome-Wide DNA Methylome and Transcriptome Analysis of Ovaries from Hu Sheep with High and Low Prolific.
LAPTM4B facilitates tumor growth and induces autophagy in hepatocellular carcinoma.
Helicobacter pylori infection promotes epithelial-to-mesenchymal transition of gastric cells by upregulating LAPTM4B.
PtdIns(4,5)P2 signaling regulates ATG14 and autophagy.
LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.
A kinase-independent role for EGF receptor in autophagy initiation.
Yao X, Li F, Wei Z, Ei-Samahy MA, Feng X, Yang F, Wang F
Frontiers in cell and developmental biology 2022;10:820558
Frontiers in cell and developmental biology 2022;10:820558
LAPTM4B facilitates tumor growth and induces autophagy in hepatocellular carcinoma.
Wang F, Wu H, Zhang S, Lu J, Lu Y, Zhan P, Fang Q, Wang F, Zhang X, Xie C, Yin Z
Cancer management and research 2019;11:2485-2497
Cancer management and research 2019;11:2485-2497
Helicobacter pylori infection promotes epithelial-to-mesenchymal transition of gastric cells by upregulating LAPTM4B.
Zhou S, Chen H, Yuan P, Shi N, Wang X, Hu J, Liu L
Biochemical and biophysical research communications 2019 Jun 30;514(3):893-900
Biochemical and biophysical research communications 2019 Jun 30;514(3):893-900
PtdIns(4,5)P2 signaling regulates ATG14 and autophagy.
Tan X, Thapa N, Liao Y, Choi S, Anderson RA
Proceedings of the National Academy of Sciences of the United States of America 2016 Sep 27;113(39):10896-901
Proceedings of the National Academy of Sciences of the United States of America 2016 Sep 27;113(39):10896-901
LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.
Milkereit R, Persaud A, Vanoaica L, Guetg A, Verrey F, Rotin D
Nature communications 2015 May 22;6:7250
Nature communications 2015 May 22;6:7250
A kinase-independent role for EGF receptor in autophagy initiation.
Tan X, Thapa N, Sun Y, Anderson RA
Cell 2015 Jan 15;160(1-2):145-60
Cell 2015 Jan 15;160(1-2):145-60
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The LAPTM4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LAPTM4B. This antibody recognizes human,mouse,rat antigen. The LAPTM4B antibody has been validated for the following applications: ELISA, WB analysis.