Tissue expression
Cell line expression
Protein structure
UBE2D3
Ubiquitin conjugating enzyme E2 D3UbcH5C
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. [provided by RefSeq, Jan 2017]
Top validated antibodies |
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| Proteintech Group | 9 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| LSBio | Monoclonal |
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| antibodies-online | Monoclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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