BS1877

antibody from Bioworld Technology, Inc
Targeting: AKAP10 D-AKAP2, MGC9414, PRKA10
Provider product page for BS1877
Western blot
Immunohistochemistry

Antibody data

Product number
BS1877 - Provider product page
Provider
Bioworld Technology, Inc
Product name
AKAP 10 (R27) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1-50 of Human AKAP 10.
Description
AKAP 10 (A kinase anchor protein 10), also known as PRKA10 or D-AKAP2 (dual-specific A kinase-anchoring protein 2), is a 662 amino acid mitochondrial membrane protein that belongs to the AKAP family. AKAP 10 is a dual specificity protein that binds to both type I and type II regulatory subunits of PKA and anchors them to the plasma membrane or the mitochondria. When anchored to the mitochondria, PKA can phosphorylate and, thus, inactivate the proapoptotic protein Bad. This suggests that AKAP 10 indirectly regulates Bad-induced apoptosis by mediating the mitochondrial attachment of PKA. Additionally, AKAP 10 may facilitate G-protein coupled signal transduction and could act as an adaptor in the assembly of multiprotein complexes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
AKAP10 protein structure - BS1877 shown in red.