ABIN863203

antibody from antibodies-online

Targeting: SCNN1B ENaCbeta

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN863203

Provider

antibodies-online

Product name

anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 617-638) antibody

Antibody type

Polyclonal

Antigen

AA617-638 of the rat sequence

Description

Affinity Purified

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 617-638

Vial size

100 μg

Concentration

1 mg/mL

Storage

-20°C

References

Submitted references

Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease.

Zhang Y, Sun Y, Ding G, Huang S, Zhang A, Jia Z
Scientific reports 2015 Jul 24;5:12480

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Intersubunit conformational changes mediate epithelial sodium channel gating.

Collier DM, Tomkovicz VR, Peterson ZJ, Benson CJ, Snyder PM
The Journal of general physiology 2014 Oct;144(4):337-48

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Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.

Hye Khan MA, Pavlov TS, Christain SV, Neckář J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD
Clinical science (London, England : 1979) 2014 Oct;127(7):463-74

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Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension.

Ramkumar N, Stuart D, Rees S, Hoek AV, Sigmund CD, Kohan DE
American journal of physiology. Renal physiology 2014 Oct 15;307(8):F931-8

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Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption.

Pavlov TS, Levchenko V, Staruschenko A
The Journal of biological chemistry 2014 Oct 10;289(41):28651-9

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Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice.

Vitzthum H, Seniuk A, Schulte LH, Müller ML, Hetz H, Ehmke H
The Journal of physiology 2014 Mar 1;592(5):1139-57

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Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.

Davies M, Fraser SA, Galic S, Choy SW, Katerelos M, Gleich K, Kemp BE, Mount PF, Power DA
American journal of physiology. Renal physiology 2014 Jul 1;307(1):F96-F106

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Double knockout of carbonic anhydrase II (CAII) and Na(+)-Cl(-) cotransporter (NCC) causes salt wasting and volume depletion.

Xu J, Barone S, Brooks MB, Soleimani M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(7):173-83

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ENaC γ-expressing astrocytes in the circumventricular organs, white matter, and ventral medullary surface: sites for Na+ regulation by glial cells.

Miller RL, Loewy AD
Journal of chemical neuroanatomy 2013 Nov;53:72-80

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Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct.

Pavlov TS, Ilatovskaya DV, Levchenko V, Li L, Ecelbarger CM, Staruschenko A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jul;27(7):2723-32

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Adenylyl cyclase VI mediates vasopressin-stimulated ENaC activity.

Roos KP, Bugaj V, Mironova E, Stockand JD, Ramkumar N, Rees S, Kohan DE
Journal of the American Society of Nephrology : JASN 2013 Feb;24(2):218-27

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The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation.

Edinger RS, Bertrand CA, Rondandino C, Apodaca GA, Johnson JP, Butterworth MB
PloS one 2012;7(9):e46593

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Regional differences in rat conjunctival ion transport activities.

Yu D, Thelin WR, Rogers TD, Stutts MJ, Randell SH, Grubb BR, Boucher RC
American journal of physiology. Cell physiology 2012 Oct 1;303(7):C767-80

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Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.

van der Lubbe N, Lim CH, Meima ME, van Veghel R, Rosenbaek LL, Mutig K, Danser AH, Fenton RA, Zietse R, Hoorn EJ
Pflugers Archiv : European journal of physiology 2012 Jun;463(6):853-63

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Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure.

Soleimani M, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H
Proceedings of the National Academy of Sciences of the United States of America 2012 Aug 14;109(33):13368-73

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Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex.

Ilatovskaya DV, Pavlov TS, Levchenko V, Negulyaev YA, Staruschenko A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Aug;25(8):2688-99

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Aberrant ENaC activation in Dahl salt-sensitive rats.

Kakizoe Y, Kitamura K, Ko T, Wakida N, Maekawa A, Miyoshi T, Shiraishi N, Adachi M, Zhang Z, Masilamani S, Tomita K
Journal of hypertension 2009 Aug;27(8):1679-89

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Effect of [Cl(-)]i on ENaC activity from mouse cortical collecting duct cells.

Gu Y
Journal of cellular physiology 2008 Aug;216(2):453-7

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The role of alpha-, beta-, and gamma-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid.

Elias N, Rafii B, Rahman M, Otulakowski G, Cutz E, O'Brodovich H
American journal of physiology. Lung cellular and molecular physiology 2007 Sep;293(3):L537-45

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Subunits of the epithelial sodium channel family are differentially expressed in the retina of mice with ocular hypertension.

Dyka FM, May CA, Enz R
Journal of neurochemistry 2005 Jul;94(1):120-8

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Multiple epithelial Na+ channel domains participate in subunit assembly.

Bruns JB, Hu B, Ahn YJ, Sheng S, Hughey RP, Kleyman TR
American journal of physiology. Renal physiology 2003 Oct;285(4):F600-9

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The ENaC channel is required for normal epidermal differentiation.

Mauro T, Guitard M, Behne M, Oda Y, Crumrine D, Komuves L, Rassner U, Elias PM, Hummler E
The Journal of investigative dermatology 2002 Apr;118(4):589-94