DPAB15701

antibody from Creative Diagnostics

Targeting: TMBIM6 BAXI1, BI-1, TEGT

Western blot (Recommended by provider)

Antibody Data

Product number

DPAB15701

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPAB15701, RRID:AB_2431964

Product name

Anti-Bl-1 polyclonal antibody

Antibody type

Polyclonal

Description

BI-1 (Bax inhibitor 1), also designated testis enhanced gene transcript (TEGT), is a regulator of cell death pathways controlled by Bcl-2 and Bax. BI-1 is an integral membrane protein containing six membrane-spanning segments and is predominantly localized to intracellular membranes, similar to Bcl-2 family proteins. The human protein contains 237 amino acids. BI-1 can interact with Bcl-2 and Bcl-XL When overexpressed in mammalian cells, BI-1 suppresses apoptosis induced by Bax, etoposide, staurosporine and growth factor deprivation. BI-1 antisense induces apoptosis.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _g

Concentration

0.2 mg/ml

Storage

-20°C