Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
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- Product number
- ABIN108563 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Centromere Protein E, 312kDa (CENPE) antibody
- Antibody type
- Monoclonal
- Description
- Affinity purified by ion exchange chromatography
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1H12
- Vial size
- 50 μL
Submitted references Midbody assembly and its regulation during cytokinesis.
Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores.
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.
Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes.
Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.
Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin.
Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function.
PIASgamma is required for faithful chromosome segregation in human cells.
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function.
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.
Hu CK, Coughlin M, Mitchison TJ
Molecular biology of the cell 2012 Mar;23(6):1024-34
Molecular biology of the cell 2012 Mar;23(6):1024-34
Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores.
Serio G, Margaria V, Jensen S, Oldani A, Bartek J, Bussolino F, Lanzetti L
Proceedings of the National Academy of Sciences of the United States of America 2011 Oct 18;108(42):17337-42
Proceedings of the National Academy of Sciences of the United States of America 2011 Oct 18;108(42):17337-42
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.
Kim Y, Holland AJ, Lan W, Cleveland DW
Cell 2010 Aug 6;142(3):444-55
Cell 2010 Aug 6;142(3):444-55
Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes.
Stimpson KM, Song IY, Jauch A, Holtgreve-Grez H, Hayden KE, Bridger JM, Sullivan BA
PLoS genetics 2010 Aug 12;6(8)
PLoS genetics 2010 Aug 12;6(8)
Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.
Townsend K, Mason H, Blackford AN, Miller ES, Chapman JR, Sedgwick GG, Barone G, Turnell AS, Stewart GS
The Journal of biological chemistry 2009 Dec 4;284(49):33939-48
The Journal of biological chemistry 2009 Dec 4;284(49):33939-48
Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin.
Cheng TS, Hsiao YL, Lin CC, Yu CT, Hsu CM, Chang MS, Lee CI, Huang CY, Howng SL, Hong YR
The Journal of biological chemistry 2008 Jan 25;283(4):2454-64
The Journal of biological chemistry 2008 Jan 25;283(4):2454-64
Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function.
Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, Khuri FR, Giannakakou P, Marcus AI
Molecular cancer therapeutics 2007 Apr;6(4):1317-28
Molecular cancer therapeutics 2007 Apr;6(4):1317-28
PIASgamma is required for faithful chromosome segregation in human cells.
Díaz-Martínez LA, Giménez-Abián JF, Azuma Y, Guacci V, Giménez-Martín G, Lanier LM, Clarke DJ
PloS one 2006 Dec 20;1:e53
PloS one 2006 Dec 20;1:e53
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function.
Chang P, Coughlin M, Mitchison TJ
Nature cell biology 2005 Nov;7(11):1133-9
Nature cell biology 2005 Nov;7(11):1133-9
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.
Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW
The EMBO journal 1991 May;10(5):1245-54
The EMBO journal 1991 May;10(5):1245-54
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