25746-1-AP

antibody from Proteintech Group

Targeting: DIS3L DIS3L1, FLJ38088, KIAA1955, MGC4562

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

25746-1-AP

Provider

Proteintech Group

Product name

DIS3L antibody

Antibody type

Polyclonal

Description

DIS3L antibody (Cat. #25746-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Cytoplasmic DIS3 is an exosome-independent endoribonuclease with catalytic activity toward circular RNAs.

Latini C, Eichlinger J, Fuchs AL, Zhai SN, Ho-Xuan H, Lehmann G, Glažar P, Rajewsky N, Bruckmann A, Yang L, Sprangers R, Meister G
Cell reports 2025 Jun 24;44(6):115769

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DIS3L, cytoplasmic exosome catalytic subunit, is essential for development but not cell viability in mice.

Brouze M, Szpila M, Czerwińska A, Antczak W, Mroczek S, Kuliński TM, Hojka-Osińska A, Cysewski D, Gewartowska O, Adamska D, Gruchota J, Borsuk E, Dziembowski A
RNA (New York, N.Y.) 2025 Apr 16;31(5):646-662

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Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.

Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JN, Dos Santos Souza C, Zhang S, Castelli L, Hautbergue G, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J
Life science alliance 2023 Jan;6(1)

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

K-562 cells were subjected to SDS PAGE followed by western blot with 25746-1-AP( DIS3L Antibody) at dilution of 1:100

Other comments

WB

Appendix

25746-1-AP.pdf

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