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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- HPA041805 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA041805, RRID:AB_10796783
- Product name
- Anti-DIS3L
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DIS3L, Gene description: DIS3 like exosome 3'-5' exoribonuclease, Alternative Gene Names: DIS3L1, FLJ38088, KIAA1955, MGC4562, Validated applications: ICC, IHC, Uniprot ID: Q8TF46, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references NMD-degradome sequencing reveals ribosome-bound intermediates with 3′-end non-templated nucleotides
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target
Kurosaki T, Miyoshi K, Myers J, Maquat L
Nature Structural & Molecular Biology 2018;25(10):940-950
Nature Structural & Molecular Biology 2018;25(10):940-950
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans
Kalisiak K, Kuliński T, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A
Nucleic Acids Research 2016
Nucleic Acids Research 2016
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target
Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny R, Gruchota J, Owczarek E, Kalisiak K, Dziembowski A
Nucleic Acids Research 2013;42(2):1270-1290
Nucleic Acids Research 2013;42(2):1270-1290
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & centrosome.
- Sample type
- Human
