Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 55110-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55110-1-AP, RRID:AB_10859943
- Product name
- USP22 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP22 antibody (Cat. #55110-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma.
Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Targeting USP22 with miR‑30‑5p to inhibit the hypoxia‑induced expression of PD‑L1 in lung adenocarcinoma cells.
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury.
Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses.
AGEs-RAGE system down-regulates Sirt1 through the ubiquitin-proteasome pathway to promote FN and TGF-β1 expression in male rat glomerular mesangial cells.
Tang Y, Wang T, Gu L, Xu Y, Yang Z, Zhu W, Zhang Q, Luo J, Cao J, Jiao Y
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma.
Zeng K, Xie W, Wang C, Wang S, Liu W, Su Y, Lin L, Zou R, Sun G, Zhou B, Wang M, Luan R, Bai Y, Huo Y, Kato S, Zhong X, Zhao Y
Cell death & disease 2023 Mar 11;14(3):194
Cell death & disease 2023 Mar 11;14(3):194
Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.
Han Z, Liu M, Xie Y, Zeng K, Zhan Z, Chen Y, Wang L, Chen X, Luo Y, Zeng Y, Zhan H, Lin Y, Zhang K, Zhu X, Liu S, Luo X, Zhou A
Cell death discovery 2022 Nov 4;8(1):445
Cell death discovery 2022 Nov 4;8(1):445
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Ren D, Sun Y, Li D, Wu H, Jin X
Molecular oncology 2022 Mar;16(5):1200-1217
Molecular oncology 2022 Mar;16(5):1200-1217
Targeting USP22 with miR‑30‑5p to inhibit the hypoxia‑induced expression of PD‑L1 in lung adenocarcinoma cells.
Hua X, Chu H, Wang C, Shi X, Wang A, Zhang Z
Oncology reports 2021 Oct;46(4)
Oncology reports 2021 Oct;46(4)
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
Xiao Y, Liu S, Li J, Dai W, Tang W, Xiang L, Zhang W, Lin J, Wang J, Wu X, Liu G, Liu Y, Chen Y, Zhu H, Wang Y, Lin Z, Yang Q, Chen T, Sun Y, Li A, Xiong J, Wang J
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L
Nature communications 2019 Jul 24;10(1):3304
Nature communications 2019 Jul 24;10(1):3304
Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury.
Ji AL, Li T, Zu G, Feng DC, Li Y, Wang GZ, Yao JH, Tian XF
World journal of gastroenterology 2019 Feb 21;25(7):824-836
World journal of gastroenterology 2019 Feb 21;25(7):824-836
Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses.
Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin FX, Cui J
Science advances 2018 May;4(5):eaar2824
Science advances 2018 May;4(5):eaar2824
AGEs-RAGE system down-regulates Sirt1 through the ubiquitin-proteasome pathway to promote FN and TGF-β1 expression in male rat glomerular mesangial cells.
Huang KP, Chen C, Hao J, Huang JY, Liu PQ, Huang HQ
Endocrinology 2015 Jan;156(1):268-79
Endocrinology 2015 Jan;156(1):268-79
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP22 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human USP22. This antibody recognizes human, mouse, rat antigen. The USP22 antibody has been validated for the following applications: ELISA, WB analysis.