13451-1-AP

antibody from Proteintech Group

Targeting: GPD1

Provider product page for 13451-1-AP

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [16]
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Validations
Western blot [1]

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Product number: 13451-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13451-1-AP, RRID:AB_10646471
Product name: GPD1 antibody
Antibody type: Polyclonal
Description: GPD1 antibody (Cat. #13451-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

GPD1 protein structure - 13451-1-AP shown in red.

Submitted references CTRP9 ameliorates heart failure with preserved ejection fraction by regulating lipid metabolism.

Xin J, Liu R, Deng M, Song Y, Cui Y, Gao J, Zhang B, Feng L, Mu X, Cui J, Li H, Zhu L, Sun Y, Yi W
Journal of translational medicine 2026 Jan 7;24(1):228

GPD1-mediated neuronal lipotoxicity drives aconitine-induced mitochondrial collapse and lethality.

Jiang C, Hu W, Deng S, Huang Y, Wang L, Yang Z, Li Y, Li P, Wu H
Chemico-biological interactions 2026 Apr 29;434:112104

Identification and Validation of Lipid Metabolism-Related Biomarkers GPD1 and CEBPD in Metabolic Dysfunction-Associated Steatohepatitis.

Zhou J, Xiao C, Huang B, Chen F
Journal of inflammation research 2025;18:14805-14823

Astragaloside IV alleviates radiation-induced heart disease by regulating energy metabolism.

Li Q, Zhang S, Li Y, Yao N, Feng Y, Yang G, Wang Y, Dai S, Cheng S, Zhou T, Wang X, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157135

VCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8(+)T cells function in the HCC microenvironment.

Cheng C, Zha Q, Sun L, Cui T, Guo X, Xing C, Chen Z, Ji C, Liang S, Tao S, Chu J, Wu C, Chu Q, Gu X, Zhang N, Fu Y, Deng S, Zhu Y, Wang J, Liu Y, Liu L
Signal transduction and targeted therapy 2025 Jan 24;10(1):26

Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation.

Petrovic D, Slade L, Paikopoulos Y, D'Andrea D, Savic N, Stancic A, Miljkovic JL, Vignane T, Drekolia MK, Mladenovic D, Sutulovic N, Refeyton A, Kolakovic M, Jovanovic VM, Zivanovic J, Miler M, Vellecco V, Brancaleone V, Bucci M, Casey AM, Yu C, Kasarla SS, Smith KW, Kalfe-Yildiz A, Stenzel M, Miranda-Vizuete A, Hergenröder R, Phapale P, Stanojlovic O, Ivanovic-Burmazovic I, Vlaski-Lafarge M, Bibli SI, Murphy MP, Otasevic V, Filipovic MR
Cell metabolism 2025 Feb 4;37(2):542-556.e14

Proteomic profile of human sinoatrial and atrioventricular nodes in comparison to working myocardium.

Krawczyk-Ożóg A, Stachowicz A, Szoniec G, Batko J, Stachyra K, Bolechała F, Strona M, Wołkow PP, Yin Z, Dobrzynski H, Hołda MK
Scientific reports 2025 Feb 28;15(1):7238

Si-Ni-San promotes liver regeneration by maintaining hepatic oxidative equilibrium and glucose/lipid metabolism homeostasis.

Yang X, Zhang J, Li Y, Hu H, Li X, Ma T, Zhang B
Journal of ethnopharmacology 2024 May 23;326:117918

Genistein and metformin regulate glycerol kinase and the enzymes of glycerol 3-phosphate shuttle in a differential manner in myocytes, hepatocytes and adipocytes.

Syngkli S, Singh SK, Rani RM, Das B
International journal of biological macromolecules 2024 Jun;270(Pt 1):132296

Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9.

Li Y, Yang X, Bao T, Sun X, Li X, Zhu H, Zhang B, Ma T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155166

Astragaloside IV and cycloastragenol promote liver regeneration through regulation of hepatic oxidative homeostasis and glucose/lipid metabolism.

Li Y, Yang X, Li X, Wang S, Chen P, Ma T, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156165

Identification of mouse soleus muscle proteins altered in response to changes in gravity loading.

Ino Y, Ohira T, Kumagai K, Nakai Y, Akiyama T, Moriyama K, Takeda Y, Saito T, Ryo A, Inaba Y, Hirano H, Kimura Y
Scientific reports 2023 Sep 22;13(1):15768

Angiotensin II induces podocyte metabolic reprogramming from glycolysis to glycerol-3-phosphate biosynthesis.

Luo Z, Chen Z, Zhu Z, Hao Y, Feng J, Luo Q, Zhang Z, Yang X, Hu J, Liang W, Ding G
Cellular signalling 2022 Nov;99:110443

A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria.

Wu S, Mao C, Kondiparthi L, Poyurovsky MV, Olszewski K, Gan B
Proceedings of the National Academy of Sciences of the United States of America 2022 Jun 28;119(26):e2121987119

Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis.

Zhang W, He X, Yin H, Cao W, Lin T, Chen W, Diao W, Ding M, Hu H, Mo W, Zhang Q, Guo H
Journal of hematology & oncology 2022 Jul 14;15(1):93

Glucose enhances catecholamine-stimulated lipolysis via increased glycerol-3-phosphate synthesis in 3T3-L1 adipocytes and rat adipose tissue.

Takeuchi N, Higashida K, Li X, Nakai N
Molecular biology reports 2021 Sep;48(9):6269-6276

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The GPD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GPD1. This antibody recognizes human, mouse, rat antigen. The GPD1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 13451-1-AP.pdf

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