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- Product number
- 16455-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16455-1-AP, RRID:AB_2127263
- Product name
- INTS12 antibody
- Antibody type
- Polyclonal
- Description
- INTS12 antibody (Cat. #16455-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint.
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Human mutations in integrator complex subunits link transcriptome integrity to brain development.
Blears D, Lou J, Fong N, Mitter R, Sheridan RM, He D, Dirac-Svejstrup AB, Bentley D, Svejstrup JQ
Molecular cell 2024 Dec 19;84(24):4790-4807.e11
Molecular cell 2024 Dec 19;84(24):4790-4807.e11
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
Kuang H, Li Y, Wang Y, Shi M, Duan R, Xiao Q, She H, Liu Y, Liang Q, Teng Y, Zhou M, Liang D, Li Z, Wu L
Cell reports 2023 Dec 26;42(12):113445
Cell reports 2023 Dec 26;42(12):113445
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ
Nature communications 2022 Oct 13;13(1):6054
Nature communications 2022 Oct 13;13(1):6054
Human mutations in integrator complex subunits link transcriptome integrity to brain development.
Oegema R, Baillat D, Schot R, van Unen LM, Brooks A, Kia SK, Hoogeboom AJM, Xia Z, Li W, Cesaroni M, Lequin MH, van Slegtenhorst M, Dobyns WB, de Coo IFM, Verheijen FW, Kremer A, van der Spek PJ, Heijsman D, Wagner EJ, Fornerod M, Mancini GMS
PLoS genetics 2017 May;13(5):e1006809
PLoS genetics 2017 May;13(5):e1006809
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INTS12 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human INTS12. This antibody recognizes human, mouse, rat antigen. The INTS12 antibody has been validated for the following applications: ELISA, WB analysis.
