Antibody data
- Antibody Data
- Antigen structure
- References [33]
- Comments [0]
- Validations [0]
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- Product number
- 66777-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TOM20 antibody
- Antibody type
- Monoclonal
- Description
- TOM20 antibody (Cat. #66777-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1D6F5
- Vial size
- 20ul, 150ul
Submitted references Melatonin alleviates glyphosate-induced testosterone synthesis inhibition via targeting mitochondrial function in roosters.
Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Design and Synthesis of 3-(2H-Chromen-3-yl)-5-aryl-1,2,4-oxadiazole Derivatives as Novel Toll-like Receptor 2/1 Agonists That Inhibit Lung Cancer In Vitro and In Vivo.
Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.
Kynurenine in IDO1(high) cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer.
Overexpression of SESN1 improves mitochondrial damage and mitophagy, a potential therapeutic strategy for cognitive dysfunction after anaesthesia.
Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis.
Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats.
SARS-CoV-2 Spike Protein S1 Domain Accelerates α-Synuclein Phosphorylation and Aggregation in Cellular Models of Synucleinopathy.
Mitochondrial calcium uniporter promotes mitophagy by regulating the PINK1/Parkin pathway in caerulein‑treated pancreatic ductal epithelial cells in vitro.
Induction of therapeutic immunity and cancer eradication through biofunctionalized liposome-like nanovesicles derived from irradiated-cancer cells.
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion.
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
Loss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway.
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Recombinant measles virus vaccine rMV-Hu191 exerts an oncolytic effect on esophageal squamous cell carcinoma via caspase-3/GSDME-mediated pyroptosis.
Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.
Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis.
Tunneling nanotubes-based intercellular mitochondrial trafficking as a novel therapeutic target in dry eye.
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons.
AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye.
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics.
WDR87 interacts with CFAP47 protein in the middle piece of spermatozoa flagella to participate in sperm tail assembly.
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Structural insight into the SAM-mediated assembly of the mitochondrial TOM core complex.
Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation.
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
Ren YL, Liang Q, Lian CY, Zhang W, Wang L
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123828
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123828
Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.
Quirion L, Robert A, Boulais J, Huang S, Bernal Astrain G, Strakhova R, Jo CH, Kherdjemil Y, Faubert D, Thibault MP, Kmita M, Baskin JM, Gingras AC, Smith MJ, Côté JF
Journal of cell science 2024 May 1;137(9)
Journal of cell science 2024 May 1;137(9)
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Liu J, Gao Y, Zhang H, Hao Z, Zhou G, Wen H, Su Q, Tong C, Yang X, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Design and Synthesis of 3-(2H-Chromen-3-yl)-5-aryl-1,2,4-oxadiazole Derivatives as Novel Toll-like Receptor 2/1 Agonists That Inhibit Lung Cancer In Vitro and In Vivo.
Wang Y, Cheng X, Liu X, Xu J, Wang L, Zhang S, Liu S, Peng T
Journal of medicinal chemistry 2024 Mar 28;67(6):4583-4602
Journal of medicinal chemistry 2024 Mar 28;67(6):4583-4602
Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.
Quirion L, Robert A, Boulais J, Huang S, Bernal Astrain G, Strakhova R, Jo CH, Kherdjemil Y, Thibault MP, Faubert D, Kmita M, Baskin JM, Gingras AC, Smith MJ, Cote JF
bioRxiv : the preprint server for biology 2024 Mar 25;
bioRxiv : the preprint server for biology 2024 Mar 25;
Kynurenine in IDO1(high) cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer.
Ying X, Zheng X, Zhang X, Yin Y, Wang X
Journal of translational medicine 2024 Mar 11;22(1):267
Journal of translational medicine 2024 Mar 11;22(1):267
Overexpression of SESN1 improves mitochondrial damage and mitophagy, a potential therapeutic strategy for cognitive dysfunction after anaesthesia.
Sun L, Hong X, Wang D, Li Y
The European journal of neuroscience 2024 Jan;59(2):208-219
The European journal of neuroscience 2024 Jan;59(2):208-219
Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis.
Gao Y, Mi N, Wu W, Zhao Y, Fan F, Liao W, Ming Y, Guan W, Bai C
Journal of extracellular vesicles 2024 Feb;13(2):e12410
Journal of extracellular vesicles 2024 Feb;13(2):e12410
Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats.
Liang JH, Yu H, Xia CP, Zheng YH, Zhang Z, Chen Y, Raza MA, Wu L, Yan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117006
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117006
SARS-CoV-2 Spike Protein S1 Domain Accelerates α-Synuclein Phosphorylation and Aggregation in Cellular Models of Synucleinopathy.
Wang J, Dai L, Deng M, Xiao T, Zhang Z, Zhang Z
Molecular neurobiology 2024 Apr;61(4):2446-2458
Molecular neurobiology 2024 Apr;61(4):2446-2458
Mitochondrial calcium uniporter promotes mitophagy by regulating the PINK1/Parkin pathway in caerulein‑treated pancreatic ductal epithelial cells in vitro.
Lei Y, Yang HY, Meng N, Qin YY, Xu MT, Xiang XL, Liu L, Tang GD
Experimental and therapeutic medicine 2024 Apr;27(4):147
Experimental and therapeutic medicine 2024 Apr;27(4):147
Induction of therapeutic immunity and cancer eradication through biofunctionalized liposome-like nanovesicles derived from irradiated-cancer cells.
Deng S, Wang J, Hu Y, Sun Y, Yang X, Zhang B, Deng Y, Wei W, Zhang Z, Wen L, Qin Y, Huang F, Sheng Y, Wan C, Yang K
Journal of nanobiotechnology 2024 Apr 8;22(1):156
Journal of nanobiotechnology 2024 Apr 8;22(1):156
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Zhang H, Wang H, Hu Y, Gao Y, Chen J, Meng Y, Qiu Y, Hu R, Liao P, Li M, He Y, Liang Z, Xie X, Li Y
Cancer letters 2024 Apr 28;588:216802
Cancer letters 2024 Apr 28;588:216802
Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion.
Knippler CM, Arnst JL, Robinson IE, Matsuk V, Khatib TO, Harvey RD, Shanmugam M, Mouw JK, Fu H, Ganesh T, Marcus AI
iScience 2024 Apr 19;27(4):109591
iScience 2024 Apr 19;27(4):109591
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Zhang Q, Shen X, Yuan X, Huang J, Zhu Y, Zhu T, Zhang T, Wu H, Wu Q, Fan Y, Ni J, Meng L, He A, Shi C, Li H, Hu Q, Wang J, Chang C, Huang F, Li F, Chen M, Liu A, Ye S, Zheng M, Fang H
Nature communications 2024 Apr 13;15(1):3213
Nature communications 2024 Apr 13;15(1):3213
Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans.
Lv M, Tang D, Yu H, Geng H, Zhou Y, Shao Z, Li K, Gao Y, Guo S, Xu C, Tan Q, Liu C, Guo R, Wu H, Duan Z, Zhang J, Wang G, Hua R, Fu F, Wang K, Xu Y, Zhou P, Wei Z, Zhang F, Cao Y, He X
International journal of biological sciences 2023;19(2):393-411
International journal of biological sciences 2023;19(2):393-411
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
Mu N, Wang Y, Li X, Du Z, Wu Y, Su M, Wang Y, Sun X, Su L, Liu X
Cell death & disease 2023 Sep 30;14(9):645
Cell death & disease 2023 Sep 30;14(9):645
Loss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway.
Chen T, Li D, Wang Y, Shen X, Dong A, Dong C, Duan K, Ren J, Li W, Shu G, Yang J, Xie Y, Qian F, Zhou J
British journal of cancer 2023 Oct;129(8):1261-1273
British journal of cancer 2023 Oct;129(8):1261-1273
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, Li J, Li Q, Zhong Z, Zhang M, Yuan Q, Hu H, Wang S, Hu MM, Cai C, Wu GS, Jiang C, Zhang YL, Zhang CS, Zhang J
The EMBO journal 2023 Oct 16;42(20):e113743
The EMBO journal 2023 Oct 16;42(20):e113743
Recombinant measles virus vaccine rMV-Hu191 exerts an oncolytic effect on esophageal squamous cell carcinoma via caspase-3/GSDME-mediated pyroptosis.
Wu A, Li Z, Wang Y, Chen Y, Peng J, Zhu M, Li Y, Song H, Zhou D, Zhang C, Lv Y, Zhao Z
Cell death discovery 2023 May 19;9(1):171
Cell death discovery 2023 May 19;9(1):171
Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.
Baringer SL, Lukacher AS, Palsa K, Kim H, Lippmann ES, Spiegelman VS, Simpson IA, Connor JR
bioRxiv : the preprint server for biology 2023 May 17;
bioRxiv : the preprint server for biology 2023 May 17;
Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis.
Zhong S, Chen W, Wang B, Gao C, Liu X, Song Y, Qi H, Liu H, Wu T, Wang R, Chen B
Redox biology 2023 Jul;63:102760
Redox biology 2023 Jul;63:102760
Tunneling nanotubes-based intercellular mitochondrial trafficking as a novel therapeutic target in dry eye.
Jiang D, Xu W, Peng F, Sun Y, Pan C, Yu J, Zheng Q, Chen W
Experimental eye research 2023 Jul;232:109497
Experimental eye research 2023 Jul;232:109497
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Xu L, Cai J, Li C, Yang M, Duan T, Zhao Q, Xi Y, Sun L, He L, Tang C, Sun L
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):58
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):58
Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons.
Chen Z, Chai E, Mou Y, Roda RH, Blackstone C, Li XJ
Brain : a journal of neurology 2022 Nov 21;145(11):4016-4031
Brain : a journal of neurology 2022 Nov 21;145(11):4016-4031
AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye.
Peng F, Jiang D, Xu W, Sun Y, Zha Z, Tan X, Yu J, Pan C, Zheng Q, Chen W
Investigative ophthalmology & visual science 2022 Nov 1;63(12):18
Investigative ophthalmology & visual science 2022 Nov 1;63(12):18
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics.
Shin YY, Seo Y, Oh SJ, Ahn JS, Song MH, Kang MJ, Oh JM, Lee D, Kim YH, Sung ES, Kim HS
Journal of pineal research 2022 Jan;72(1):e12779
Journal of pineal research 2022 Jan;72(1):e12779
WDR87 interacts with CFAP47 protein in the middle piece of spermatozoa flagella to participate in sperm tail assembly.
Liao HQ, Guo ZY, Huang LH, Liu G, Lu JF, Zhang YF, Xing XW
Molecular human reproduction 2022 Dec 28;29(1)
Molecular human reproduction 2022 Dec 28;29(1)
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Lu L, Liu JB, Wang JQ, Lian CY, Wang ZY, Wang L
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Structural insight into the SAM-mediated assembly of the mitochondrial TOM core complex.
Wang Q, Guan Z, Qi L, Zhuang J, Wang C, Hong S, Yan L, Wu Y, Cao X, Cao J, Yan J, Zou T, Liu Z, Zhang D, Yan C, Yin P
Science (New York, N.Y.) 2021 Sep 17;373(6561):1377-1381
Science (New York, N.Y.) 2021 Sep 17;373(6561):1377-1381
Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation.
Mollo N, Esposito M, Aurilia M, Scognamiglio R, Accarino R, Bonfiglio F, Cicatiello R, Charalambous M, Procaccini C, Micillo T, Genesio R, Calì G, Secondo A, Paladino S, Matarese G, De Vita G, Conti A, Nitsch L, Izzo A
Biology 2021 Jun 30;10(7)
Biology 2021 Jun 30;10(7)
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
Ou W, Liang Y, Qin Y, Wu W, Xie M, Zhang Y, Zhang Y, Ji L, Yu H, Li T
Redox biology 2021 Jul;43:101994
Redox biology 2021 Jul;43:101994
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