Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- AF921 - Provider product page
- Provider
- R&D Systems
- Product name
- Human BAMBI/NMA Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human BAMBI/NMA in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q13145
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease.
C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling.
TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease.
Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors.
Sun SW, Chen L, Zhou M, Wu JH, Meng ZJ, Han HL, Miao SY, Zhu CC, Xiong XZ
Respiratory research 2019 Feb 6;20(1):26
Respiratory research 2019 Feb 6;20(1):26
C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling.
Lee S, Lee MJ, Zhang J, Yu GR, Kim DG
Experimental & molecular medicine 2016 Dec 2;48(12):e275
Experimental & molecular medicine 2016 Dec 2;48(12):e275
TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease.
Zhang JC, Chen G, Chen L, Meng ZJ, Xiong XZ, Liu HJ, Jin Y, Tao XN, Wu JH, Sun SW
Scientific reports 2016 Aug 23;6:31911
Scientific reports 2016 Aug 23;6:31911
Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors.
Luo X, Hutley LJ, Webster JA, Kim YH, Liu DF, Newell FS, Widberg CH, Bachmann A, Turner N, Schmitz-Peiffer C, Prins JB, Yang GS, Whitehead JP
Diabetes 2012 Jan;61(1):124-36
Diabetes 2012 Jan;61(1):124-36
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- BAMBI/NMA in Human Kidney. BAMBI/NMA was detected in immersion fixed paraffin-embedded sections of human kidney using Goat Anti-Human BAMBI/NMA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF921) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in tubular epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.