Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NBP2-75779-20ug - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal GP2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 20 ug
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: GP2 Antibody (GP2/1803) [NBP2-75779] - Formalin-fixed, paraffin-embedded Human Pancreas stained with GP2 Mouse Monoclonal Antibody (GP2/1803).