HPA039951

antibody from Atlas Antibodies

Targeting: TBCK HSPC302, MGC16169

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA039951

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA039951, RRID:AB_10795300

Product name

Anti-TBCK

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human TBCK, Gene description: TBC1 domain containing kinase, Alternative Gene Names: HSPC302, MGC16169, Validated applications: WB, IHC, Uniprot ID: Q8TEA7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Heterozygous variants in TBCK cause a mild neurologic syndrome in humans and mice

Nair D, Diaz‐Rosado A, Varella‐Branco E, Ramos I, Black A, Angireddy R, Park J, Murali S, Yoon A, Ciesielski B, O'Brien W, Passos‐Bueno M, Bhoj E
American Journal of Medical Genetics Part A 2023;191(10):2508-2517

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In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

Gillingham A, Bertram J, Begum F, Munro S
eLife 2019;8

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Recessive Inactivating Mutations in TBCK, Encoding a Rab GTPase-Activating Protein, Cause Severe Infantile Syndromic Encephalopathy

Chong J, Caputo V, Phelps I, Stella L, Worgan L, Dempsey J, Nguyen A, Leuzzi V, Webster R, Pizzuti A, Marvin C, Ishak G, Ardern-Holmes S, Richmond Z, Bamshad M, Ortiz-Gonzalez X, Tartaglia M, Chopra M, Doherty D
The American Journal of Human Genetics 2016;98(4):772-781