Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1673633 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Linker For Activation of T Cells (LAT) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human LAT, different from the related mouse and rat sequences by six amino acids.Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect.
LAT regulates gammadelta T cell homeostasis and differentiation.
Hundt M, Tabata H, Jeon MS, Hayashi K, Tanaka Y, Krishna R, De Giorgio L, Liu YC, Fukata M, Altman A
Immunity 2006 May;24(5):513-22
Immunity 2006 May;24(5):513-22
LAT regulates gammadelta T cell homeostasis and differentiation.
Nuñez-Cruz S, Aguado E, Richelme S, Chetaille B, Mura AM, Richelme M, Pouyet L, Jouvin-Marche E, Xerri L, Malissen B, Malissen M
Nature immunology 2003 Oct;4(10):999-1008
Nature immunology 2003 Oct;4(10):999-1008
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