Antibody data

Product number
Ab112829 - Provider product page
Provider
Aladdin Scientific
Product name
Recombinant LAT Antibody
Antibody type
Recombinant
Description
Rabbit anti Human LAT Antibody, Recombinant, could be used for WB, IHC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionRequired for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 217-234
Vial size
100_l,10_l,1ml,50_l
Concentration
0,2 mg/ml
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
LAT protein structure - Ab112829 shown in red.