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- Product number
- 13103-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13103-2-AP, RRID:AB_2272213
- Product name
- TSEN2 antibody
- Antibody type
- Polyclonal
- Description
- TSEN2 antibody (Cat. #13103-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references An unknown essential function of tRNA splicing endonuclease is linked to the integrated stress response and intron debranching.
Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly.
CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
Hurtig JE, van Hoof A
Genetics 2023 May 26;224(2)
Genetics 2023 May 26;224(2)
Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly.
Breuss MW, Sultan T, James KN, Rosti RO, Scott E, Musaev D, Furia B, Reis A, Sticht H, Al-Owain M, Alkuraya FS, Reuter MS, Abou Jamra R, Trotta CR, Gleeson JG
American journal of human genetics 2016 Jul 7;99(1):228-35
American journal of human genetics 2016 Jul 7;99(1):228-35
CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
Schaffer AE, Eggens VR, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu XD, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG
Cell 2014 Apr 24;157(3):651-63
Cell 2014 Apr 24;157(3):651-63
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The TSEN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TSEN2. This antibody recognizes human, mouse, rat antigen. The TSEN2 antibody has been validated for the following applications: ELISA, WB analysis.
