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- References [14]
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- Product number
- 14816-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14816-1-AP, RRID:AB_2162250
- Product name
- PEX16 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PEX16 antibody (Cat. #14816-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exosomes from human umbilical cord mesenchymal stem cells protect aortas in Db/db mice characterized by combination of metabolomics and proteomics.
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
Knockdown of PEX16 Induces Autophagic Degradation of Peroxisomes.
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis.
PEX16 contributions to peroxisome import and metabolism revealed by viable Arabidopsis pex16 mutants.
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.
Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress.
Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes.
Peroxisomes protect lymphoma cells from HDAC inhibitor-mediated apoptosis.
Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice.
Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells.
Ling MY, Yang XC, Yu N, Song YP, Zheng YJ, Tang CM, Ding WJ, Sun Y, Yan R, Wang SP, Li XH, Gao HQ, Zhang Z, Xing YQ
Archives of biochemistry and biophysics 2022 Nov 30;731:109430
Archives of biochemistry and biophysics 2022 Nov 30;731:109430
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
Mu Y, Maharjan Y, Kumar Dutta R, Wei X, Kim JH, Son J, Park C, Park R
PloS one 2021;16(2):e0245799
PloS one 2021;16(2):e0245799
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, Pende M, Sabio G, Sabatini DM, Efeyan A
Nature communications 2021 Jun 16;12(1):3660
Nature communications 2021 Jun 16;12(1):3660
Knockdown of PEX16 Induces Autophagic Degradation of Peroxisomes.
Wei X, Maharjan Y, Dorotea D, Dutta RK, Kim D, Kim H, Mu Y, Park C, Park R
International journal of molecular sciences 2021 Jul 26;22(15)
International journal of molecular sciences 2021 Jul 26;22(15)
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis.
Cui W, Liu D, Gu W, Chu B
Cell death and differentiation 2021 Aug;28(8):2536-2551
Cell death and differentiation 2021 Aug;28(8):2536-2551
PEX16 contributions to peroxisome import and metabolism revealed by viable Arabidopsis pex16 mutants.
Burkhart SE, Llinas RJ, Bartel B
Journal of integrative plant biology 2019 Jul;61(7):853-870
Journal of integrative plant biology 2019 Jul;61(7):853-870
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.
Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ
The Journal of clinical investigation 2019 Feb 1;129(2):694-711
The Journal of clinical investigation 2019 Feb 1;129(2):694-711
Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress.
Piao L, Dorotea D, Jiang S, Koh EH, Oh GT, Ha H
Antioxidants & redox signaling 2019 Dec 20;31(18):1339-1351
Antioxidants & redox signaling 2019 Dec 20;31(18):1339-1351
Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes.
Schönenberger MJ, Kovacs WJ
Methods in molecular biology (Clifton, N.J.) 2017;1595:13-26
Methods in molecular biology (Clifton, N.J.) 2017;1595:13-26
Peroxisomes protect lymphoma cells from HDAC inhibitor-mediated apoptosis.
Dahabieh MS, Ha Z, Di Pietro E, Nichol JN, Bolt AM, Goncalves C, Dupéré-Richer D, Pettersson F, Mann KK, Braverman NE, Del Rincón SV, Miller WH Jr
Cell death and differentiation 2017 Nov;24(11):1912-1924
Cell death and differentiation 2017 Nov;24(11):1912-1924
Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Hofer DC, Pessentheiner AR, Pelzmann HJ, Schlager S, Madreiter-Sokolowski CT, Kolb D, Eichmann TO, Rechberger G, Bilban M, Graier WF, Kratky D, Bogner-Strauss JG
Biochimica et biophysica acta. Molecular and cell biology of lipids 2017 Mar;1862(3):358-368
Biochimica et biophysica acta. Molecular and cell biology of lipids 2017 Mar;1862(3):358-368
Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Walter KM, Schönenberger MJ, Trötzmüller M, Horn M, Elsässer HP, Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Köfeler HC, Krek W, Kovacs WJ
Cell metabolism 2014 Nov 4;20(5):882-897
Cell metabolism 2014 Nov 4;20(5):882-897
Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice.
Kovacs WJ, Charles KN, Walter KM, Shackelford JE, Wikander TM, Richards MJ, Fliesler SJ, Krisans SK, Faust PL
Biochimica et biophysica acta 2012 Jun;1821(6):895-907
Biochimica et biophysica acta 2012 Jun;1821(6):895-907
Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells.
Yonekawa S, Furuno A, Baba T, Fujiki Y, Ogasawara Y, Yamamoto A, Tagaya M, Tani K
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 2;108(31):12746-51
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 2;108(31):12746-51
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PEX16 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PEX16. This antibody recognizes human, mouse, rat antigen. The PEX16 antibody has been validated for the following applications: ELISA, WB analysis.
