PA5-58727

antibody from Invitrogen Antibodies

Targeting: LARP4 PP13296

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-58727

Provider

Invitrogen Antibodies

Product name

LARP4 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Immunogen sequence: KTNAAAMNMG RPFQKNRVKP QFRSSGGSEH STEGSVSLGD GQLNRYSSRN FPAERHNPTV TGHQEQTYLQ KETSTLQVEQ NGDYGRGR Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 27%.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.2 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface.

Gabrovsek L, Collins KB, Aggarwal S, Saunders LM, Lau HT, Suh D, Sancak Y, Trapnell C, Ong SE, Smith FD, Scott JD
The Journal of biological chemistry 2020 Jul 31;295(31):10749-10765

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Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription.

Gilbertson S, Federspiel JD, Hartenian E, Cristea IM, Glaunsinger B
eLife 2018 Oct 3;7

Immunocytochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of LARP4 in human cell line A-431 shows positivity in cytoplasm. Samples were probed using a LARP4 Polyclonal Antibody (Product # PA5-58727).

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorecent analysis of LARP4 in human cell line A-431 using LARP4 Polyclonal Antibody (Product # PA5-58727). Staining shows localization to cytosol.

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of LARP4 in human skin using LARP4 Polyclonal Antibody (Product # PA5-58727) shows no positivity in squamous epithelial cells as expected.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of LARP4 in human placenta using LARP4 Polyclonal Antibody (Product # PA5-58727) shows strong cytoplasmic positivity in trophoblastic cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of LARP4 in human kidney using LARP4 Polyclonal Antibody (Product # PA5-58727) shows moderate cytoplasmic positivity in cells in tubules.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of LARP4 in human liver using LARP4 Polyclonal Antibody (Product # PA5-58727) shows moderate granular cytoplasmic positivity in hepatocytes.

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

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