ABIN363049

antibody from antibodies-online

Targeting: SMAD3 HsT17436, JV15-2, MADH3

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN363049

Provider

antibodies-online

Product name

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 423-427) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 423-427 (C-S-S-V-S) derived from Human Smad3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 423-427

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.

Wordinger RJ, Fleenor DL, Hellberg PE, Pang IH, Tovar TO, Zode GS, Fuller JA, Clark AF
Investigative ophthalmology & visual science 2007 Mar;48(3):1191-200

---

Cthrc1 is a novel inhibitor of transforming growth factor-beta signaling and neointimal lesion formation.

LeClair RJ, Durmus T, Wang Q, Pyagay P, Terzic A, Lindner V
Circulation research 2007 Mar 30;100(6):826-33

---

3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins.

Seong HA, Jung H, Kim KT, Ha H
The Journal of biological chemistry 2007 Apr 20;282(16):12272-89

---

Endofin acts as a Smad anchor for receptor activation in BMP signaling.

Shi W, Chang C, Nie S, Xie S, Wan M, Cao X
Journal of cell science 2007 Apr 1;120(Pt 7):1216-24